Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376093 | 0.87 | GSK3B (0.63) | GSK3BCDC7PDE10A | |
| SCHEMBL5386527 | 0.84 | GSK3B (0.53) | GSK3BCDC7PDE10A | |
| SCHEMBL5386993 | 0.83 | GSK3B (0.48) | GSK3BCDC7NPC1LMNARAB9A | |
| SCHEMBL5390690 | 0.82 | GSK3B (0.48) | GSK3BCDC7 | |
| SCHEMBL5375203 | 0.82 | GSK3B (0.47) | GSK3BCDC7 | |
| SCHEMBL5381458 | 0.81 | CYP17A1 (0.47) | GSK3BCDC7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5376071 | 0.81 | GSK3B (0.49) | GSK3BCDC7PDE10A | |
| SCHEMBL5390451 | 0.80 | GSK3B (0.45) | GSK3BCDC7NPC1MAPTRAB9A | |
| SCHEMBL5380263 | 0.80 | GSK3B (0.48) | GSK3BCDC7PDE10A | |
| SCHEMBL5386910 | 0.80 | GSK3B (0.76) | GSK3BCDC7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |