Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.48 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380257 | 0.85 | MAPT (0.49) | GSK3BCDC7KMT2APDE10A | |
| SCHEMBL5376093 | 0.84 | GSK3B (0.63) | GSK3BCDC7KMT2APDE10A | |
| SCHEMBL5380266 | 0.81 | GSK3B (0.74) | GSK3BCDC7KMT2A | |
| SCHEMBL5386993 | 0.80 | GSK3B (0.48) | GSK3BCDC7KMT2A | |
| SCHEMBL5390690 | 0.80 | GSK3B (0.48) | GSK3BCDC7KMT2A | |
| SCHEMBL5386907 | 0.80 | GSK3B (0.48) | GSK3BCDC7PDE10A | |
| SCHEMBL5386527 | 0.79 | GSK3B (0.53) | GSK3BCDC7PDE10A | |
| SCHEMBL5376071 | 0.78 | GSK3B (0.49) | GSK3BCDC7PDE10A | |
| SCHEMBL5383560 | 0.78 | KDM4E (0.44) | GSK3BCDC7KMT2APDE10APIK3C3 | |
| SCHEMBL5399975 | 0.78 | CDC7 (0.48) | GSK3BCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |