SCHEMBL5376578

SCHEMBL5376578

Cl[Hf]1(Cl)C2C(=Cc3ccccc32)CCC2=Cc3ccccc3C21

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4337186 0.81 KDM1A (0.36) KDM1A
SCHEMBL4332387 0.78 KDM1A (0.34) KDM1A
SCHEMBL4323019 0.77 CYP11B1 (0.35) KDM1A
SCHEMBL5068718 0.71 KDM1A (0.37) KDM1A
SCHEMBL3641346 0.69 KDM1A (0.39) KDM1A
SCHEMBL577658 0.69 KDM1A (0.39) KDM1A
SCHEMBL2046288 0.69 KDM1A (0.39) KDM1A
SCHEMBL2074643 0.69 KDM1A (0.40) KDM1A
SCHEMBL3693119 0.69 KDM1A (0.36) KDM1A
SCHEMBL7204963 0.68 KDM1A (0.38) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387839-B1 COORDINATION POLYMERIZATION CATALYST CHINA PETROCHEMICAL CORPORATION (CN) 2002-05-14 US claimed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP claimed
US-7199073-B2 Resins that yield low haze films and the process for their production CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2007-04-03 US disclosed
US-20060100401-A1 Resins that yield low haze films and the process for their production CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2006-05-11 US disclosed
US-6555632-B1 Homo or copolymerization of alpha-olefin in presence of a catalyst system containing neutral halogenated metallocene catalyst, an organoaluminum compound, and an ionizing agent SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 2003-04-29 US disclosed
US-6387839-B1 COORDINATION POLYMERIZATION CATALYST CHINA PETROCHEMICAL CORPORATION (CN) 2002-05-14 US disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
US-5817725-A Process for the preparation of a catalytic system, process for the (CO) polymerization of olefins and (CO) polymers of at least one olefin SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 1998-10-06 US disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
US-5612271-A Process for the prepration of a catalytic system, process for the (co)polymerization of olefins and (co)polymers of at least one olefin SOLVAY (SOCIETE ANONYME) (BE) 1997-03-18 US disclosed