SCHEMBL4323019

SCHEMBL4323019

CC[Hf]1(CC)C2C(=Cc3ccccc32)CCC2=Cc3ccccc3C21

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
KDM1A O60341 1/20 0.33
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4337186 0.80 KDM1A (0.36) CYP11B1CYP11B2KDM1AKDM4EL3MBTL1
SCHEMBL5376578 0.77 KDM1A (0.36) KDM1A
SCHEMBL4332387 0.74 KDM1A (0.34) KDM1A
SCHEMBL6355473 0.69 CYP11B1 (0.35) CYP11B1CYP11B2KDM1AKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7899797 0.68 CYP11B1 (0.34) CYP11B1CYP11B2KDM1AKDM4EL3MBTL1
SCHEMBL4453972 0.67 DRD2 (0.35) CYP11B1CYP11B2KDM1AKDM4EL3MBTL1
SCHEMBL577658 0.66 KDM1A (0.39) KDM1A
SCHEMBL2046288 0.66 KDM1A (0.39) KDM1A
SCHEMBL3641346 0.66 KDM1A (0.39) KDM1A
SCHEMBL61248 0.66 KDM1A (0.36) CYP11B1CYP11B2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US claimed
US-5714426-A COORDINATION CATALYST COMPRISING AN ETHYLENEBIS(INDENYL)HAFNIUM AND AN ALUMINUM COMPOUND OR ALUMOXANE; ETHYLENE COPOLYMERS HAVING EXCELLENT FLOWABILITY AND NARROW MOLECULAR WEIGHT DISTRIBUTION; PACKAGING FILMS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-02-03 US claimed
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US disclosed
US-20050267273-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2005-12-01 US disclosed
EP-1231229-A2 Ethylene polymer, preparation process thereof and molded articles of the same Mitsui Chemicals, Inc. (JP) 2002-08-14 EP disclosed
US-20020107343-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2002-08-08 US disclosed
EP-0769505-B1 Olefin copolymers and processes for preparing same MITSUI CHEMICALS INC (JP) 2000-05-10 EP disclosed
EP-0955321-A2 Olefin copolymers and processes for preparing same Mitsui Chemicals, Inc. (JP) 1999-11-10 EP disclosed
EP-0955322-A2 Olefin copolymers and processes for preparing same Mitsui Chemicals, Inc. (JP) 1999-11-10 EP disclosed
US-5916988-A COPOLYMERS WITH ALPHA-OLEFINS THAT ARE EXCELLENT IN FLOWABILITY MITSUI CEHMICALS, INC. (JP) 1999-06-29 US disclosed
EP-0685498-B1 Olefin copolymers and processes for preparing same MITSUI CHEMICALS INC (JP) 1999-05-26 EP disclosed
US-5714426-A COORDINATION CATALYST COMPRISING AN ETHYLENEBIS(INDENYL)HAFNIUM AND AN ALUMINUM COMPOUND OR ALUMOXANE; ETHYLENE COPOLYMERS HAVING EXCELLENT FLOWABILITY AND NARROW MOLECULAR WEIGHT DISTRIBUTION; PACKAGING FILMS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-02-03 US disclosed
US-5639842-A NARROW MOLECULAR WEIGHT DISTRIBUTION, EXCELLENT IN FLOWABILITY, LOW MELTING, HEAT-SEALING AND ANTIBLOCKING PROPERTIES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-06-17 US disclosed
EP-0769505-A1 Olefin copolymers and processes for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-04-23 EP disclosed
US-5525689-A USING A COORDINATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-06-11 US disclosed
EP-0685496-A1 Olefin copolymers and processes for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-06 EP disclosed
EP-0685498-A1 Olefin copolymers and processes for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-06 EP disclosed
US-5218071-A Narrow molecular weight distribution; excellent flowability MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-06-08 US disclosed
EP-0495099-A1 OLEFIN COPOLYMER AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-07-22 EP disclosed