SCHEMBL4337186

SCHEMBL4337186

C[Hf]1(C)C2C(=Cc3ccccc32)CCC2=Cc3ccccc3C21

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.36
DRD2 P14416 5/20 0.33
DRD4 P21917 5/20 0.33
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP19A1 P11511 1/20 0.30
PRCP P42785 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5376578 0.81 KDM1A (0.36) KDM1A
SCHEMBL4323019 0.80 CYP11B1 (0.35) KDM1ACYP11B1CYP11B2KDM4EL3MBTL1
SCHEMBL4332387 0.78 KDM1A (0.34) KDM1A
SCHEMBL7640892 0.72
SCHEMBL7599525 0.72 HTR2A (0.31)
SCHEMBL17387214 0.70
SCHEMBL577658 0.69 KDM1A (0.39) KDM1A
SCHEMBL3641346 0.69 KDM1A (0.39) KDM1A
SCHEMBL2046288 0.69 KDM1A (0.39) KDM1A
SCHEMBL61248 0.69 KDM1A (0.36) KDM1ADRD2DRD4CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US claimed
EP-0426638-B2 Addition of aluminium alkyl for improved metallocene catalyst FINA TECHNOLOGY (US) 2005-03-02 EP claimed
US-5714426-A COORDINATION CATALYST COMPRISING AN ETHYLENEBIS(INDENYL)HAFNIUM AND AN ALUMINUM COMPOUND OR ALUMOXANE; ETHYLENE COPOLYMERS HAVING EXCELLENT FLOWABILITY AND NARROW MOLECULAR WEIGHT DISTRIBUTION; PACKAGING FILMS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-02-03 US claimed
JP-2022307-A None JP disclosed
JP-2022308-A None JP disclosed
JP-2255812-A None JP disclosed
JP-2173016-A None JP disclosed
US-8373011-B2 Used in a base oil of lubricant having good low temperature fluidity, low evaporativity, and thermal stability and oxidation stability IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US disclosed
EP-0945471-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU KOSAN CO (JP) 2009-05-13 EP disclosed
US-20080146469-A1 Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2008-06-19 US disclosed
US-5525689-A USING A COORDINATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-06-11 US disclosed
EP-0685496-A1 Olefin copolymers and processes for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-06 EP disclosed
EP-0685498-A1 Olefin copolymers and processes for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-06 EP disclosed
US-5218071-A Narrow molecular weight distribution; excellent flowability MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-06-08 US disclosed
EP-0495099-A1 OLEFIN COPOLYMER AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-07-22 EP disclosed
JP-H02255812-A PROPYLENE COPOLYMER AND ITS PRODUCTION MITSUI PETROCHEM IND LTD 1990-10-16 JP disclosed
JP-H02173016-A HEAT-SEALING AGENT MITSUI PETROCHEM IND LTD 1990-07-04 JP disclosed
JP-H0222307-A CATALYST FOR OLEFIN POLYMERIZATION AND POLYMERIZATION OF OLEFIN MITSUI PETROCHEM IND LTD 1990-01-25 JP disclosed
JP-H0222308-A CATALYST FOR OLEFIN POLYMERIZATION AND POLYMERIZATION OF OLEFIN MITSUI PETROCHEM IND LTD 1990-01-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146469-A1 Process for producing saturated aliphatic hydrocarbon compound, and lubricant composition ALOX15, ALOX12, ALOX15B KDM1A 3253/4885DRD2 318/4885DRD4 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.