SCHEMBL5377189

SCHEMBL5377189

C=Cc1ccc(O)cc1CCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.56
ALOX5 P09917 5/20 0.49
CYP3A4 P08684 3/20 0.49
TP53 P04637 2/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
ERAP1 Q9NZ08 1/20 0.43
ESR1 P03372 4/20 0.43
ESR2 Q92731 2/20 0.43
PTGS2 P35354 4/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432899 0.89 TYR (0.42) TYRALOX5CYP3A4TP53MAPT
SCHEMBL5388042 0.89 TYR (0.42) TYRALOX5CYP3A4TP53MAPT
SCHEMBL29263435 0.86 TYR (0.61) TYRALOX5CYP3A4TP53MAPT
SCHEMBL3431324 0.83 TYR (0.56) TYRALOX5CYP3A4TP53MAPT
SCHEMBL5382204 0.82 ESR1 (0.42) TYRMEN1KMT2AESR1ESR2
SCHEMBL3626784 0.81 TLR7 (0.40) TYRTP53MAPTHTTKMT2A
SCHEMBL12802098 0.81 THRA (0.44) CYP3A4MEN1HTTKMT2AGPR84
SCHEMBL10426037 0.81 TYR (0.37) TYRALOX5CYP3A4TP53MAPT
SCHEMBL3679575 0.79 TYR (0.36) TYRMEN1HTTKMT2AALDH1A1
SCHEMBL28780014 0.79 THRB (0.39) TYRMEN1KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103980648-A Directed self assembly copolymer composition and related methods DOW GLOBAL TECHNOLOGIES LLC 2014-08-13 CN claimed
JP-58079920-A None JP disclosed
JP-58079919-A None JP disclosed
CN-103571252-B Thermal annealing process ROHM & HAAS ELECT MAT 2015-06-17 CN disclosed
CN-103571253-B High temperature thermal annealing process ROHM & HAAS ELECT MAT 2015-06-03 CN disclosed
CN-103980648-A Directed self assembly copolymer composition and related methods DOW GLOBAL TECHNOLOGIES LLC 2014-08-13 CN disclosed
CN-103665726-A Composition and method for preparing pattern on a substrate ROHM & HAAS ELECT MAT 2014-03-26 CN disclosed
CN-103571252-A Thermal annealing process ROHM & HAAS ELECT MAT 2014-02-12 CN disclosed
CN-103571253-A High temperature thermal annealing process ROHM & HAAS ELECT MAT 2014-02-12 CN disclosed
CN-100406481-C Resist polymer and resist composition MITSUBISHI RAYON CO (JP) 2008-07-30 CN disclosed
US-7202359-B2 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2007-04-10 US disclosed
CN-1745114-A Resist polymer and resist composition MITSUBISHI RAYON CO (JP) 2006-03-08 CN disclosed
CN-1234706-C Nitrogen-oxygen heterocyclic compound and preparation method thereof CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2006-01-04 CN disclosed
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2005-04-21 US disclosed
CN-1490318-A Nitrogen-oxygen heterocyclic compound and preparation method thereof 长春人造树脂厂股份有限公司 2004-04-21 CN disclosed
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-08 US disclosed
US-6211328-B1 IN PRESENCE OF AN ACID GUN EI CHEMICAL INDUSTRY CO., LTD (JP) 2001-04-03 US disclosed
JP-S5879920-A INHIBITOR AGAINST BLOOD PLATELET AGGREGATION KANEGAFUCHI CHEM IND CO LTD 1983-05-13 JP disclosed
JP-S5879919-A ANTIPHLOGISTIC, ANALGESIC AND ANTIPYRETIC KANEGAFUCHI CHEM IND CO LTD 1983-05-13 JP disclosed
JP-S05879919-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 TYR 485/4885ALOX5 137/4885CYP3A4 1456/4885
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 TYR 314/4885ALOX5 112/4885CYP3A4 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.