Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044019 | 0.87 | PTPN1 (0.77) | PTPN1MAOAMAOBPTPN2BCHE | |
| SCHEMBL31292056 | 0.87 | PTPN1 (0.77) | PTPN1MAOAMAOBPTPN2BCHE | |
| SCHEMBL29952901 | 0.87 | PTPN1 (0.77) | PTPN1MAOAMAOBPTPN2BCHE | |
| SCHEMBL7026584 | 0.80 | PTPN1 (0.64) | PTPN1MAOAMAOBPTPN2BCHE | |
| SCHEMBL28914825 | 0.78 | PTPN1 (0.63) | PTPN1ALOX15ALDH1A1POLBMAPT | |
| SCHEMBL5363245 | 0.74 | PTPN1 (1.00) | PTPN1MAOAMAOBPTPN2ALDH1A1 | |
| SCHEMBL911098 | 0.74 | ALDH1A1 (0.68) | PTPN1MAOAMAOBPTPN2ALDH1A1 | |
| SCHEMBL29952420 | 0.74 | ALDH1A1 (0.68) | PTPN1MAOAMAOBPTPN2ALDH1A1 | |
| SCHEMBL29958044 | 0.74 | PTPN1 (0.77) | PTPN1MAOAMAOBPTPN2ALDH1A1 | |
| SCHEMBL29956322 | 0.74 | PTPN1 (0.61) | PTPN1MAOAMAOBPTPN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836142-B | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-12-12 | — | — | CN | claimed |
| CN-116836142-A | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-10-03 | — | — | CN | claimed |
| CN-115819431-B | Synthesis method and application of benzopyrone condensed hydroindole compounds | 广州大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-119977949-A | Chromone bisindole derivative and preparation method and application thereof | 重庆文理学院 | 2025-05-13 | — | — | CN | disclosed |
| CN-119930565-A | Hydroxy flavonoid derivative and preparation method and application thereof | 重庆文理学院 | 2025-05-06 | — | — | CN | disclosed |
| EP-4306106-A1 | NITRO-CONTAINING COMPOUNDS, COMPOSITIONS AND USES THEREOF | Universidade de Aveiro (PT) | 2024-01-17 | — | — | EP | disclosed |
| CN-116836142-B | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-116836142-B | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-116836142-A | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116836142-A | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-115819431-A | Synthesis method and application of benzopyrone-fused hydrogenated indole compound | 广州大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. | 2005-09-08 | — | — | US | disclosed |
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6545031-B1 | Carboxyalkenylpyrazolylbenzene derivatives, such as (E)-alpha-((5-(2-((2-carboxyphenyl)methoxy)-4-methoxyphenyl) -1-ethyl-1H-pyrazol-4-yl)methylene)-6-methoxy-1,3-benzodioxole -5-propanoic acid | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-0843551-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000053313-A2 | LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| EP-0843551-A4 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0843551-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997004773-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | FRK, PTK2, DSTYK | PTPN1 882/4885MAOA 1231/4885MAOB 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.