Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381545 | 0.93 | CDC7 (0.59) | CDC7GSK3BALDH1A1HPGDHSD17B10 | |
| SCHEMBL7395689 | 0.91 | MAPK14 (0.48) | CDC7GSK3BALDH1A1HPGDHSD17B10 | |
| SCHEMBL5399995 | 0.91 | MAPK14 (0.54) | CDC7GSK3BMAPK13PRKD3CSNK1A1 | |
| SCHEMBL5380873 | 0.91 | MAPK14 (0.49) | CDC7GSK3BALDH1A1HPGDHSD17B10 | |
| SCHEMBL5384093 | 0.91 | GCGR (0.56) | ALDH1A1HPGDMAPK13MAPK1MAPK12 | |
| SCHEMBL5383543 | 0.87 | PKN1 (0.53) | CDC7GSK3BNPY5RPKN1PKN2 | |
| SCHEMBL5376057 | 0.86 | KMT2A (0.54) | CDC7ALDH1A1HPGDMAPTNPY5R | |
| SCHEMBL5381418 | 0.86 | CYP19A1 (0.54) | CDC7GSK3BALDH1A1HPGDMAPT | |
| SCHEMBL5380413 | 0.85 | NPC1 (0.56) | CDC7ALDH1A1MAPTALOX15PKN1 | |
| SCHEMBL5381446 | 0.85 | GSK3B (0.47) | CDC7GSK3BALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |