Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380592 | 0.89 | FFAR1 (0.50) | FFAR1FFAR4 | |
| SCHEMBL5377364 | 0.87 | FFAR1 (0.41) | FFAR1FFAR4CYP4F2CYP4A11PTPN1 | |
| SCHEMBL5372367 | 0.84 | FFAR1 (0.40) | FFAR1FFAR4L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL5372016 | 0.84 | L3MBTL1 (0.42) | FFAR1FFAR4L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL5377258 | 0.84 | ALDH1A1 (0.48) | FFAR1FFAR4L3MBTL1 | |
| SCHEMBL5385614 | 0.83 | CYP4F2 (0.48) | L3MBTL1CYP4F2CYP4A11PTPN1 | |
| SCHEMBL5385157 | 0.82 | FFAR1 (0.44) | FFAR1FFAR4CYP4F2CYP4A11S1PR5 | |
| SCHEMBL5377471 | 0.82 | FFAR1 (0.40) | FFAR1FFAR4CYP4F2CYP4A11PTPN1 | |
| SCHEMBL5376983 | 0.82 | PTPN11 (0.41) | FFAR1FFAR4L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL5385770 | 0.82 | ALOX5AP (0.43) | FFAR1FFAR4CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |
| EP-1457490-A1 | 5-membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1228067-B1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |