SCHEMBL5377811

SCHEMBL5377811

CCCCCC1=CCC(c2ccc(-c3ccc(OCC)c(F)c3F)cc2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.33
FGFR2 P21802 1/20 0.33
FPR2 P25090 1/20 0.32
ESR1 P03372 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14356143 0.87 CYP11B2 (0.31)
SCHEMBL7648448 0.86 ACE2 (0.34) ACE2
SCHEMBL15381668 0.85 CCNT1 (0.34) FGFR1FGFR2FPR2ESR1NAAA
SCHEMBL15381682 0.84 FGFR2 (0.36) FGFR1FGFR2FPR2ESR1NAAA
SCHEMBL15723090 0.81
SCHEMBL10008126 0.80 FPR2 (0.33) FGFR1FGFR2FPR2NAAA
SCHEMBL15381584 0.80 FPR2 (0.33) FGFR1FGFR2FPR2ESR1NAAA
SCHEMBL11933149 0.80 FGFR1 (0.33) FGFR1FGFR2FPR2NAAA
SCHEMBL10008471 0.79 PTPN11 (0.36) FGFR1FGFR2FPR2NAAA
SCHEMBL10008476 0.79 PTPN11 (0.36) FGFR1FGFR2FPR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294371-B2 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-13 US disclosed
US-7294371-B2 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-13 US disclosed
US-20050104039-A1 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050104039-A1 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed CACNA1I, TBRG4, CACNA1E FGFR1 1047/4885FGFR2 1401/4885FPR2 640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.