SCHEMBL5377907

SCHEMBL5377907

c1ccc(OCSCOc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.55
TAAR1 Q96RJ0 1/20 0.48
ALDH1A1 P00352 1/20 0.48
RECQL P46063 1/20 0.48
ALOX15 P16050 1/20 0.46
CHRNB2 P17787 2/20 0.45
CHRNB4 P30926 2/20 0.45
CHRNA3 P32297 2/20 0.45
CHRNA7 P36544 2/20 0.45
CHRNA4 P43681 2/20 0.45
LTA4H P09960 2/20 0.44
HTR1B P28222 2/20 0.43
TSHR P16473 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10739619 0.85 KCNA3 (0.46) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL7956346 0.85 KCNA3 (0.46) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL3360240 0.81 KCNA3 (0.52) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL7894721 0.79 KCNA3 (0.50) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL10911324 0.77 ALDH1A1 (0.50) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL609214 0.74
SCHEMBL8671561 0.74 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLCHRNB2
SCHEMBL497461 0.73 KCNA3 (0.63) KCNA3TAAR1ALDH1A1RECQLALOX15
SCHEMBL27962 0.73 KCNA3 (0.82) KCNA3TAAR1ALDH1A1RECQLCHRNB2
SCHEMBL6535231 0.72 KCNA3 (0.68) KCNA3TAAR1ALDH1A1RECQLCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103114109-B Method for synthesizing chiral sulfoxide from thioether under catalytic action of Rhodococcus UNIV CHANGZHOU 2014-07-09 CN claimed
CN-103114109-A Method for synthesizing chiral sulfoxide from thioether under catalytic action of Rhodococcus UNIV CHANGZHOU 2013-05-22 CN claimed
WO-2024041535-A1 NANO-COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 赣州和美药业股份有限公司 2024-02-29 WO disclosed
CN-103114109-B Method for synthesizing chiral sulfoxide from thioether under catalytic action of Rhodococcus UNIV CHANGZHOU 2014-07-09 CN disclosed
CN-103114109-A Method for synthesizing chiral sulfoxide from thioether under catalytic action of Rhodococcus UNIV CHANGZHOU 2013-05-22 CN disclosed
US-7259219-B2 Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof DOW GLOBAL TECHNOLOGIES INC. (US) 2007-08-21 US disclosed
US-7074870-B2 Styrene polymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. (US) 2006-07-11 US disclosed
EP-1495059-B1 LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF DOW GLOBAL TECHNOLOGIES INC (US) 2006-05-24 EP disclosed
US-20060025547-A1 Styrene polymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. (US) 2006-02-02 US disclosed
US-6965004-B2 Ethylene-styrene copolymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. (US) 2005-11-15 US disclosed
US-6933355-B2 Ethylene-styrene copolymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. (US) 2005-08-23 US disclosed
US-20050165192-A1 Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof DOW GLOBAL TECHNOLOGIES, INC. 2005-07-28 US disclosed
EP-1495059-A1 LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2005-01-12 EP disclosed
US-20040214717-A1 Ethylene-styrene copolymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. 2004-10-28 US disclosed
US-20040214714-A1 low molecular weight polymers with unique bulk properties SYMYX TECHNOLOGIES, INC. 2004-10-28 US disclosed
US-6794514-B2 FOR PRODUCTION OF LOW MOLECULAR WEIGHT POLYMERS SYMYX TECHNOLOGIES, INC. 2004-09-21 US disclosed
US-20030232717-A1 Ethylene-styrene copolymers and phenol-triazole type complexes, catalysts, and processes for polymerizing SYMYX TECHNOLOGIES, INC. 2003-12-18 US disclosed
WO-2003087178-A1 LOW MOLECULAR WEIGHT COPOLYMER OF ETHYLENE AND VINYL AROMATIC MONOMER AND USES THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2003-10-23 WO disclosed
WO-2003087177-A2 ETHYLENE-STYRENE COPOLYMERS, COMPLEXES AND CATALYSTS WITH PHENOL-TRIAZOLE LIGANDS AND PROCESSES FOR POLYMERIZING THEREWITH SYMYX TECHNOLOGIES, INC. (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232717-A1 Ethylene-styrene copolymers and phenol-triazole type complexes, catalysts, and processes for polymerizing STK33, STK11, ELL KCNA3 2347/4885TAAR1 1454/4885ALDH1A1 3289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.