Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377907 | 0.81 | KCNA3 (0.55) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL11285757 | 0.78 | KCNA3 (0.58) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL1148270 | 0.77 | NQO1 (0.70) | LTA4HLMNAALDH1A1PKM | |
| SCHEMBL7894721 | 0.77 | KCNA3 (0.50) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13461370 | 0.77 | DRD2 (0.47) | ALDH1A1KCNH2 | |
| SCHEMBL7244289 | 0.77 | KCNA3 (0.62) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL6305305 | 0.75 | NQO1 (0.35) | — | |
| SCHEMBL10911324 | 0.75 | ALDH1A1 (0.50) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9668483 | 0.75 | ALDH1A1 (0.44) | CHRNA7ALDH1A1 | |
| SCHEMBL13978367 | 0.75 | AGXT (0.64) | ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611790-A | Preparation method of methylthio methyl phenyl ether | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-17 | — | — | CN | claimed |
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSTY | 2023-01-26 | — | — | US | disclosed |
| CN-115611790-A | Preparation method of methylthio methyl phenyl ether | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-17 | — | — | CN | disclosed |
| CN-115611790-A | Preparation method of methylthio methyl phenyl ether | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-17 | — | — | CN | disclosed |
| CN-115611790-A | Preparation method of methylthio methyl phenyl ether | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-01-17 | — | — | CN | disclosed |
| US-10344177-B2 | Under layer film-forming composition for imprints and method for forming pattern | FUJIFILM CORPORATION (JP) | 2019-07-09 | — | — | US | disclosed |
| CN-108602825-A | Purine compounds having anticancer activity | 中央研究院 | 2018-09-28 | — | — | CN | disclosed |
| CN-104114605-B | Method for polymer synthesis | 沙特阿美技术公司 | 2018-06-22 | — | — | CN | disclosed |
| US-20150258092-A1 | RIBOSOME STRUCTURE AND PROTEIN SYNTHESIS INHIBITORS | YALE UNIVERSITY (US) | 2015-09-17 | — | — | US | disclosed |
| US-8912150-B2 | Ribosome structure and protein synthesis inhibitors | MELINTA THERAPEUTICS, INC. (US) | 2014-12-16 | — | — | US | disclosed |
| EP-1308457-B1 | Ribosome structure and protein synthesis inhibitors | UNIV YALE (US) | 2013-12-04 | — | — | EP | disclosed |
| US-8470990-B2 | Ribosome structure and protein synthesis inhibitors | RIB-X PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100204253-A1 | Ribosome Structure and Protein Synthesis Inhibitors | YALE UNIVERSITY (US) | 2010-08-12 | — | — | US | disclosed |
| US-7666849-B2 | ligands that are designed to specifically kill or inhibit the growth of any target organism | RIB-X PHARMACEUTICALS, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-20050272681-A1 | ligands that are designed to specifically kill or inhibit the growth of any target organism | YALE UNIVERSITY (US) | 2005-12-08 | — | — | US | disclosed |
| US-6947845-B2 | Method of identifying molecules that bind to the large ribosomal subunit | YALE UNIVERSITY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050036997-A1 | Molecular modeling of the binding sites for anisomycin, azithromycin, erythromycin, linezolid, tylosin, carbomycin A, spiramycin, virginiamycin, sparsomycin and blasticidin using the Haloarcular marismortui large ribosomal subunit; drug design and drug screening | YALE UNIVERSITY (US) | 2005-02-17 | — | — | US | disclosed |
| EP-1308457-A1 | Ribosome structure and protein synthesis inhibitors | YALE UNIVERSITY (US) | 2003-05-07 | — | — | EP | disclosed |
| US-6207838-B1 | ELECTROLYSIS IN LIQUID SULFUR DIOXIDE | THE UNIVERSITY OF ARIZONA | 2001-03-27 | — | — | US | disclosed |
| EP-1048752-A2 | Electrochemically generated organothiating reagents and their use | ALBEMARLE CORPORATION (US) | 2000-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | LRBA, HADHA, IMPDH1 | KCNA3 4740/4885CHRNB2 4853/4885CHRNB4 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.