Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244739 | 1.00 | MMP2 (0.51) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2546161 | 0.92 | MMP1 (0.50) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2246882 | 0.92 | MMP1 (0.50) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2552852 | 0.91 | S1PR1 (0.41) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2244432 | 0.91 | S1PR1 (0.41) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL8272256 | 0.87 | NPC1 (0.51) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2549237 | 0.87 | NPC1 (0.51) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL5381528 | 0.87 | NPC1 (0.51) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2246821 | 0.87 | NPC1 (0.51) | MMP2MMP1MMP8MMP3MMP13 | |
| SCHEMBL2551610 | 0.84 | MMP1 (0.37) | MMP2MMP1MMP8HRH3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | claimed |