Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Floverine SCHEMBL2109150 | 0.87 | ALDH1A1 (0.52) | ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2 | |
| SCHEMBL18210964 | 0.87 | ALDH1A1 (0.48) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL18308830 | 0.87 | ALDH1A1 (0.48) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL1573275 | 0.87 | ALDH1A1 (0.52) | ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2 | |
| SCHEMBL10636078 | 0.87 | ALDH1A1 (0.48) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL9507394 | 0.87 | MAPT (0.50) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL2759034 | 0.85 | ALDH1A1 (0.44) | ALDH1A1RECQLTSHRTP53ALOX15 | |
| SCHEMBL28466694 | 0.84 | CNR1 (0.50) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL17046324 | 0.84 | ALDH1A1 (0.50) | ALDH1A1RECQLNR1I2GAACA12 | |
| SCHEMBL48418 | 0.84 | ALDH1A1 (0.70) | ALDH1A1RECQLNR1I2GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390643-B2 | Modified oligonucleotides comprising thiol functions and use thereof for detecting nucleic acids | ETABLISSEMENT FRANÇAIS DU SANG (FR) | 2022-07-19 | — | — | US | disclosed |
| US-11078229-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-08-03 | — | — | US | disclosed |
| US-20180265538-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2018-09-20 | — | — | US | disclosed |
| US-9896473-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | ETABLISSEMENT FRANCAIS DU SANG (FR) | 2018-02-20 | — | — | US | disclosed |
| EP-2834253-B1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-03-29 | — | — | EP | disclosed |
| EP-2859008-B1 | MODIFIED OLIGONUCLEOTIDES COMPRISING THIOL FUNCTIONS AND THE USE OF SAME FOR THE DETECTION OF NUCLEIC ACIDS | ETABLISSEMENT FRANÇAIS DU SANG (EFS) (FR) | 2017-02-22 | — | — | EP | disclosed |
| US-20150232957-A1 | MODIFIED OLIGONUCLEOTIDES COMPRISING THIOL FUNCTIONS AND USE THEREOF FOR DETECTING NUCLEIC ACIDS | ETABLISSEMENT FRANÇAIS DU SANG (FR) | 2015-08-20 | — | — | US | disclosed |
| US-20150158964-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2015-06-11 | — | — | US | disclosed |
| EP-2859008-A1 | MODIFIED OLIGONUCLEOTIDES COMPRISING THIOL FUNCTIONS AND THE USE OF SAME FOR THE DETECTION OF NUCLEIC ACIDS | Etablissement Français Du Sang (EFS) (FR) | 2015-04-15 | — | — | EP | disclosed |
| EP-2834253-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | Centre National de la Recherche Scientifique (CNRS) (FR) | 2015-02-11 | — | — | EP | disclosed |
| US-20030232973-A1 | High-affinity, low-molecular-mass displacers for ion-exchange chromatography | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2003-12-18 | — | — | US | disclosed |
| US-6632580-B2 | Hydrophilic support; recording using infrared radiation scanning radiation | FUJI PHOTO FILM CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| WO-2003074148-A1 | HIGH-AFFINITY, LOW-MOLECULAR-MASS DISPLACERS FOR ION-EXCHANGE CHROMATOGRAPHY | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030138721-A1 | For recording images by infrared scanning exposure based on digital signals; improved on-machine development quality, photosensitivity, and high printing durability | FUJIFILM CORPORATION (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1287985-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-20020031715-A1 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2002-03-14 | — | — | US | disclosed |
| EP-1160083-A2 | Lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5106885-A | Radiation curable compositions containing multifunctional vinyl ether monomers and protective coatings formed therefrom | ISP INVESTMENTS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-4859790-A | Esters of 3-tert-butyl- and 3-tert-butyl-5-alkyl-4-hydroxyphenyl (alkane) carboxylic acids with oxethylates of polyhydroxyaromatics, process for their production, and their use as stabilizers | HUELS AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0268037-A2 | 3-Tert-butyl- and, 3-tert-butyl-5-alkyl-4-hydroxyphenyl alcanoic acid ester with oxethylates of polyhydroxy aromatic compounds, process for their preparation and their use as stabilizer | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158964-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | TST, APEX1, TMT1A | ALDH1A1 329/4885RECQL 4100/4885NR1I2 4008/4885 |
| US-11390643-B2 | Modified oligonucleotides comprising thiol functions and use thereof for detecting nucleic acids | DNAJC10, TIMCC, TST | ALDH1A1 323/4885RECQL 3355/4885NR1I2 2997/4885 |
| US-20030232973-A1 | High-affinity, low-molecular-mass displacers for ion-exchange chromatography | SERPINA6, IGFBP1, FABP1 | ALDH1A1 3157/4885RECQL 2190/4885NR1I2 1349/4885 |
| US-20180265538-A1 | THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES | TST, APEX1, TMT1A | ALDH1A1 329/4885RECQL 4100/4885NR1I2 4008/4885 |
| US-11078229-B2 | Thiol compounds and the use thereof for the synthesis of modified oligonucleotides | TST, APEX1, TMT1A | ALDH1A1 329/4885RECQL 4100/4885NR1I2 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.