Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094930 | 0.89 | HTR2A (0.55) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL13463193 | 0.77 | CHUK (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDKIF11 | |
| SCHEMBL619090 | 0.76 | KDR (0.60) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL27352303 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDKDR | |
| SCHEMBL27352062 | 0.76 | LMNA (0.43) | KDM4EHTR2AHTR2CKDR | |
| SCHEMBL30667668 | 0.76 | LMNA (0.43) | KDM4EHTR2AHTR2CKDR | |
| SCHEMBL29244459 | 0.76 | PARP1 (0.41) | KDR | |
| SCHEMBL12294086 | 0.76 | PARP1 (0.60) | — | |
| SCHEMBL19037260 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL30293726 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619947-A | Benzopyrrolopiperidine class compound and application thereof | 晨伫(杭州)生物科技有限责任公司 | 2024-09-10 | — | — | CN | claimed |
| US-8969340-B2 | Methods for treating chronic pelvic pain syndrome | NORTHWESTERN UNIVERSITY (US) | 2015-03-03 | — | — | US | claimed |
| US-20130303530-A1 | METHODS FOR TREATING CHRONIC PELVIC PAIN SYNDROME WITH ANTIBODIES THAT BINDS MCP-1 OR MIP-1A | NORTHWESTERN UNIVERSITY (US) | 2013-11-14 | — | — | US | claimed |
| US-20110014205-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC PELVIC PAIN SYNDROME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-20 | — | — | US | claimed |
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-118619947-A | Benzopyrrolopiperidine class compound and application thereof | 晨伫(杭州)生物科技有限责任公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118619947-A | Benzopyrrolopiperidine class compound and application thereof | 晨伫(杭州)生物科技有限责任公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |
| CN-116789641-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |
| WO-2023031308-A1 | CCR2 INHIBITORS | ARTICA THERAPEUTICS B.V. (NL) | 2023-03-09 | — | — | WO | disclosed |
| EP-1343751-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-27 | — | — | US | disclosed |
| US-20030004151-A1 | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-01-02 | — | — | US | disclosed |
| WO-2002079151-A1 | 3-SUBSTITUTED INDOELS OR FUSED PYRROLES AS ANTAGONISTS OF THE CHEMOKINE MCP-1 (CCR2B) RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002060859-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |
| WO-2001014374-A2 | PROCESSES FOR THE PREPRATION OF EXO- AND ENDO-INDOLOTROPANES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004151-A1 | Cyclic derivatives as modulators of chemokine receptor activity | CCL11, CCR1, CCL2 | KDM4E 4656/4885ALDH1A1 1095/4885SMN1; SMN2 3732/4885 |
| US-20130303530-A1 | METHODS FOR TREATING CHRONIC PELVIC PAIN SYNDROME WITH ANTIBODIES THAT BINDS MCP-1 OR MIP-1A | CCR1, CCR2, CCL2 | KDM4E 4479/4885ALDH1A1 518/4885SMN1; SMN2 2927/4885 |
| US-20110014205-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC PELVIC PAIN SYNDROME | CCR2, CCR1, CCL2 | KDM4E 4614/4885ALDH1A1 623/4885SMN1; SMN2 2001/4885 |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | KDM4E 4236/4885ALDH1A1 296/4885SMN1; SMN2 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.