SCHEMBL5378322

SCHEMBL5378322

C=CCc1c(O)cccc1Sc1cccc(O)c1CC=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.40
GABRB2 P47870 3/20 0.40
SRD5A1 P18405 1/20 0.39
XDH P47989 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 3/20 0.36
AKR1B1 P15121 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 2/20 0.36
ALDH2 P05091 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MTNR1A P48039 1/20 0.35
ACHE P22303 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69556 0.83 GABRA1 (0.48) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL27958462 0.78 TRPA1 (0.45) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL2321816 0.78 TRPA1 (0.45) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL30023289 0.78 TRPA1 (0.45) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL10587406 0.78 GABRA1 (0.53) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL6690960 0.78 GABRA1 (0.44) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL28694886 0.77 LMNA (0.35) GABRA1GABRB2MEN1KMT2AMAPT
Hydrogen Sulfide SCHEMBL28097887 0.77 TRPA1 (0.43) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL27777553 0.77 TRPA1 (0.43) GABRA1GABRB2SRD5A1XDHMEN1
SCHEMBL11598660 0.77 GABRA1 (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4906390-A Borated diol-phenol sulfide product and lubricant compositions containing same MOBIL OIL CORPORATION (US) 1990-03-06 US claimed
US-4541942-A Borated epoxyhydrocarbon-phenol sulfide product and lubricant and fuel compositions containing same MOBIL OIL CORPORATION (US) 1985-09-17 US claimed
US-4466925-A COMPLEXING A PHENOL, AN ALKALI METAL CARBONATE AND AN ALCOHOL MOBIL OIL CORPORATION (US) 1984-08-21 US claimed
EP-0001911-B1 REACTION PRODUCT OF NICKEL THIOBIS(ALKYLPHENOLATE) AND THIOBISPHENOL OR THIOBIS(ALKYLPHENOL) AND ORGANIC COMPOSITIONS CONTAINING THE SAME MOBIL OIL CORPORATION (US) 1981-11-25 EP claimed
EP-0001911-A1 Reaction product of nickel thiobis(alkylphenolate) and thiobisphenol or thiobis(alkylphenol) and organic compositions containing the same MOBIL OIL CORPORATION (US) 1979-05-16 EP claimed
US-4151100-A RADIATION RESISTANCE, ANTISLUDGING AGENTS, ENERGY QUENCHERS MOBIL OIL CORPORATION (US) 1979-04-24 US claimed
US-4119548-A ANTIOXIDANT FOR LUBRICANTS AND PLASTICS MOBIL OIL CORPORATION (US) 1978-10-10 US claimed
EP-1313826-B1 EXTENDED DRAIN MANUAL TRANSMISSION LUBRICANTS AND CONCENTRATES LUBRIZOL CORP (US) 2007-10-17 EP disclosed
EP-1313826-A2 EXTENDED DRAIN MANUAL TRANSMISSION LUBRICANTS AND CONCENTRATES The Lubrizol Corporation (US) 2003-05-28 EP disclosed
US-6503872-B1 Metal (di)thiophosphate, organic phosphite, and alkaline earth metal salt of carboxylic acid or phenolate compound; extreme pressure lubricants; wear resistance THE LUBRIZOL CORPORATION 2003-01-07 US disclosed
WO-2002016533-A2 EXTENDED DRAIN MANUAL TRANSMISSION LUBRICANTS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 2002-02-28 WO disclosed
US-5773391-A VEGETABLE OIL, ANTIOXIDANT, METAL DEACTIVATOR OF BENZOTRIAZOLE AND HYDROXYL GROUPS THE LUBRIZOL CORPORATION (US) 1998-06-30 US disclosed
EP-0551466-B1 The use of an additive composition to improve wet filterability of lubricating compositions LUBRIZOL CORP (US) 1998-06-17 EP disclosed
US-4211663-A LUBRICANTS MOBIL OIL CORPORATION (US) 1980-07-08 US disclosed
EP-0001911-A1 Reaction product of nickel thiobis(alkylphenolate) and thiobisphenol or thiobis(alkylphenol) and organic compositions containing the same MOBIL OIL CORPORATION (US) 1979-05-16 EP disclosed
EP-0001911-A1 Reaction product of nickel thiobis(alkylphenolate) and thiobisphenol or thiobis(alkylphenol) and organic compositions containing the same MOBIL OIL CORPORATION (US) 1979-05-16 EP disclosed
US-4151100-A RADIATION RESISTANCE, ANTISLUDGING AGENTS, ENERGY QUENCHERS MOBIL OIL CORPORATION (US) 1979-04-24 US disclosed
US-4119548-A ANTIOXIDANT FOR LUBRICANTS AND PLASTICS MOBIL OIL CORPORATION (US) 1978-10-10 US disclosed
US-4119548-A ANTIOXIDANT FOR LUBRICANTS AND PLASTICS MOBIL OIL CORPORATION (US) 1978-10-10 US disclosed
US-4119548-A ANTIOXIDANT FOR LUBRICANTS AND PLASTICS MOBIL OIL CORPORATION (US) 1978-10-10 US disclosed