Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048773 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL30704256 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| Sulfamide SCHEMBL28235502 | 0.75 | KMT2A (0.61) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL205647 | 0.74 | MEN1 (0.41) | KMT2AMEN1CA1CA2CA12 | |
| SCHEMBL304541 | 0.74 | HSD17B10 (0.48) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL11565380 | 0.73 | HSD17B10 (0.52) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL29048059 | 0.72 | HSD17B10 (0.47) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL15689351 | 0.71 | KMT2A (0.48) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL10825687 | 0.71 | HSD17B10 (0.45) | KMT2AMEN1HSD17B10TDP1ALDH1A1 | |
| SCHEMBL8069994 | 0.71 | ALDH1A1 (0.46) | KMT2AMEN1HSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211696-B2 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | THE OHIO STATE UNIVERSITY (US) | 2007-05-01 | — | — | US | disclosed |
| US-20050227982-A1 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | WERBOVETZ KARL | 2005-10-13 | — | — | US | disclosed |
| EP-1560574-A2 | ANTILEISHMANIAL DINITROANILINE SULFONAMIDES WITH ACTIVITY AGAINST PARASITE TUBULIN | THE OHIO STATE UNIVERSITY (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2003090678-A2 | ANTILEISHMANIAL DINITROANILINE SULFONAMIDES WITH ACTIVITY AGAINST PARASITE TUBULIN | OHIO STATE UNIVERSITY (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227982-A1 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | TUBB, TUBB2A, TUBA1A | KMT2A 1439/4885MEN1 2883/4885F2 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.