Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylaminoethanol SCHEMBL9003859 | 0.92 | MAPT (0.71) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Diethylaminoethanol SCHEMBL4773320 | 0.91 | MAPT (0.55) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL9715505 | 0.90 | MAPT (0.52) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Diethylaminoethanol SCHEMBL10699915 | 0.88 | — | — | |
| Diethylaminoethanol SCHEMBL3114 | 0.88 | — | — | |
| SCHEMBL23117107 | 0.86 | MAPT (0.55) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL15410677 | 0.85 | MAPT (0.80) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL22749413 | 0.85 | CYP1A2 (0.52) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Diethylaminoethanol SCHEMBL20815437 | 0.85 | — | — | |
| Diethylaminoethanol SCHEMBL20293885 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369665-A1 | POROUS FILM AND METHOD OF FORMING POROUS FILM | FUJI XEROX CO., LTD. (JP) | 2017-12-28 | — | — | US | claimed |
| JP-62190078-A | — | — | None | — | — | JP | disclosed |
| US-10023528-B2 | Branched 3-phenylpropionic acid derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-07-17 | — | — | US | disclosed |
| US-20170001947-A1 | DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2017-01-05 | — | — | US | disclosed |
| US-20160264515-A1 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| EP-2914610-A2 | GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS | GlycoMimetics, Inc. (US) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014070991-A2 | E-SELECTIN ANTAGONIST COMPOUNDS AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2014-05-08 | — | — | WO | disclosed |
| EP-2414366-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | Novartis AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112520-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | NOVARTIS AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| US-7635701-B2 | Pyrimidine derivatives and their use as CB2 modulators | GLAXO GROUP LIMITED (GB) | 2009-12-22 | — | — | US | disclosed |
| US-20060293354-A1 | Pyrimidine derivatives and their use as CB2 modulators | GLAXO GROUP LIMITED (GB) | 2006-12-28 | — | — | US | disclosed |
| US-5773505-A | Polymer emulsions with bimodal molecular-weight distribution | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1998-06-30 | — | — | US | disclosed |
| US-4939191-A | High strength cured cement article and process for manufacturing the same | UBE INDUSTRIES, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| JP-S62190078-A | PRODUCTION OF CHOLINE OXIDASE | TOYOBO CO LTD | 1987-08-20 | — | — | JP | disclosed |
| US-4582842-A | Anti-asthmatic 6H-dibenz-[b,e] [1,4]oxathiepin derivatives, compositions, and method of use therefor | MERCK & CO., INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4297430-A | WHEREIN DEVELOPMENT IS CARRIED OUT IN THE PRESENCE OF A CYCLIC IMIDE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264515-A1 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | MAPT 3036/4885CYP1A2 1195/4885CYP2C9 1287/4885 |
| US-20060293354-A1 | Pyrimidine derivatives and their use as CB2 modulators | CNR2, CNR1, P2RX3 | MAPT 2894/4885CYP1A2 1273/4885CYP2C9 1187/4885 |
| US-20170001947-A1 | DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY | NR1H4, LDLR, LIPA | MAPT 3979/4885CYP1A2 4272/4885CYP2C9 4611/4885 |
| US-10023528-B2 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | MAPT 3036/4885CYP1A2 1195/4885CYP2C9 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.