SCHEMBL5379464

SCHEMBL5379464

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nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16217646 0.74 ADRB2 (0.44) ADRB2ADRB1ADRB3
SCHEMBL9436624 0.74 ADRB2 (0.44) ADRB2ADRB1ADRB3
SCHEMBL16217648 0.73 ADRB2 (0.43) ADRB2ADRB1ADRB3
SCHEMBL812981 0.71 ADRB2 (0.44) ADRB2ADRB1ADRB3
SCHEMBL2160941 0.70 ADRB2 (0.34) ADRB2ADRB1ADRB3
SCHEMBL2161806 0.65 ADRB2 (0.41) ADRB2ADRB1ADRB3
SCHEMBL2161774 0.65 ADRB2 (0.38) ADRB2ADRB1ADRB3
SCHEMBL2161830 0.64 ADRB2 (0.40) ADRB2ADRB1ADRB3
SCHEMBL13072978 0.64 ACACB (0.41)
SCHEMBL13258901 0.64 ACACB (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217698-B2 Use of mannosamine derivatives for the stimulation of neurite growth DOMPATENT VON KREISLER SELTING WERNER (DE) 2007-05-15 US disclosed
US-20050107333-A1 Use of mannosamine derivatives for the stimulation of neurite growth REUTTER WERNER (DE) 2005-05-19 US disclosed
EP-1429788-A2 USE OF MANNOSAMINE DERIVATIVES FOR THE STIMULATION OF NEURITE GROWTH Reutter, Werner (DE) 2004-06-23 EP disclosed
WO-2003028709-A2 USE OF MANNOSAMINE DERIVATIVES FOR THE STIMULATION OF NEURITE GROWTH REUTTER WERNER (DE) 2003-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107333-A1 Use of mannosamine derivatives for the stimulation of neurite growth NGF, BDNF, GAP43 ADRB2 1896/4885ADRB1 2383/4885ADRB3 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.