Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379674 | 1.00 | TAS1R3 (0.50) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL4175264 | 0.83 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL4166621 | 0.83 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL4169220 | 0.83 | TAS1R3 (0.56) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL12248802 | 0.68 | ALDH1A1 (0.40) | HPGDMEN1KMT2ALMNAPOLB | |
| SCHEMBL5273446 | 0.68 | CYP3A4 (0.47) | HPGDMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL4178594 | 0.67 | TAS1R3 (0.83) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL4176281 | 0.67 | TAS1R3 (0.83) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL5752877 | 0.67 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2HPGDMEN1 | |
| SCHEMBL5924001 | 0.67 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203142-A | Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers | SENOMYX INC (US) | 2008-06-18 | — | — | CN | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |