Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.83 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.83 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178594 | 1.00 | TAS1R3 (0.83) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL5754053 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL5752877 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL5924001 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL20662780 | 0.84 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL4175750 | 0.79 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL4175061 | 0.79 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL13928024 | 0.79 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL4178596 | 0.79 | PKM (0.64) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM | |
| SCHEMBL4166794 | 0.72 | PKM (1.00) | TAS1R3TAS1R1TAS1R2SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | TAS1R3 27/4885TAS1R1 23/4885TAS1R2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.