Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434858 | 1.00 | ESR1 (0.70) | ESR1MEN1KMT2AALOX5HSD17B1 | |
| Phenol SCHEMBL28114880 | 0.89 | TSHR (0.60) | ESR1MEN1KMT2AALOX5HSD17B1 | |
| SCHEMBL16394285 | 0.88 | TAAR1 (0.71) | ALOX5ESR2TAAR1MAOB | |
| SCHEMBL31491189 | 0.88 | TAAR1 (0.71) | ALOX5ESR2TAAR1MAOB | |
| SCHEMBL20669453 | 0.85 | TAAR1 (0.68) | ESR1MEN1KMT2AALOX5ESR2 | |
| SCHEMBL5037644 | 0.85 | HSD17B1 (0.68) | ESR1MEN1KMT2AALOX5HSD17B1 | |
| SCHEMBL1029061 | 0.84 | TSHR (0.73) | ESR1ALOX5HSD17B1HSD17B2ESR2 | |
| SCHEMBL3924021 | 0.84 | ESR2 (0.71) | ESR1ALOX5HSD17B1HSD17B2ESR2 | |
| SCHEMBL1520884 | 0.83 | TAAR1 (0.65) | ALOX5ESR2TAAR1MAOB | |
| SCHEMBL16394095 | 0.83 | TAAR1 (0.65) | ALOX5ESR2TAAR1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227043-A2 | Composite semipermeable membrane and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-01 | — | — | EP | claimed |
| CN-109503686-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108314697-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108546277-B | Novel nucleoside phosphoramidate compounds and uses thereof | 南京圣和药业股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-109790149-A | PHENOXYTRIAZOLES | 豪夫迈·罗氏有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109607826-A | The biological removal method of acute biological toxicity in ozone process | 南京理工大学 | 2019-04-12 | — | — | CN | disclosed |
| CN-109503686-A | New nucleoside phosphoramidate compound and its application | 南京圣和药业股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109415330-A | Novel difluoro keto acyl amine derivative as HTRA1 inhibitor | 豪夫迈·罗氏有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-9963480-B2 | Nucleoside phosphoramidate compound and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-05-08 | — | — | US | disclosed |
| CN-107522654-A | New α aminoamide derivatives and its medical usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-12-29 | — | — | CN | disclosed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| CN-1208403-A | Compounds | BRITISH ASTRA PHARMACEUTICALS (GB) | 1999-02-17 | — | — | CN | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |
| EP-0227043-A2 | Composite semipermeable membrane and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4483961-A | Polymeric cyclopentadiene derivatives, method for preparing and use thereof | ASHLAND OIL, INC. (US) | 1984-11-20 | — | — | US | disclosed |
| US-4482653-A | Cyclopentadiene derivatives, method for preparing, and use thereof | ASHLAND OIL, INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4464521-A | EPOXIDIZED FULVENES AS BINDER FOR AGGREGATE; FOUNDRY BINDERS | ASHLAND OIL, INC. (US) | 1984-08-07 | — | — | US | disclosed |
| US-4412088-A | CURABLE BINDER COMPOSITIONS | ASHLAND OIL, INC. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4390675-A | EPOXYFULVENE, ACID CATALYST | ASHLAND OIL, INC. (US) | 1983-06-28 | — | — | US | disclosed |