SCHEMBL5380177

SCHEMBL5380177

C1CCC(PC2CCC2)C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5388176 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5381224 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5389059 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5387267 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5392299 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5387887 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5393933 0.96 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5386201 0.96
SCHEMBL1403737 0.96 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5393504 0.92 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2831128-B1 PREPARATION OF FUNCTIONAL POLYMERS USING PHOSPHIDE INITIATORS BRIDGESTONE CORP (JP) 2016-11-30 EP disclosed
US-9163104-B2 Preparation of functional polymers using phosphide initiators BRIDGESTONE CORPORATION (JP) 2015-10-20 US disclosed
US-20150065673-A1 Preparation Of Functional Polymers Using Phosphide Initiators BRIDGESTONE CORPORATION (JP) 2015-03-05 US disclosed
EP-2831128-A1 PREPARATION OF FUNCTIONAL POLYMERS USING PHOSPHIDE INITIATORS Bridgestone Corporation (JP) 2015-02-04 EP disclosed
CN-104271618-A Preparation of functional polymers using phosphide initiators BRIDGESTONE CORP 2015-01-07 CN disclosed
WO-2013149233-A1 PREPARATION OF FUNCTIONAL POLYMERS USING PHOSPHIDE INITIATORS BRIDGESTONE CORPORATION (JP) 2013-10-03 WO disclosed
US-7214747-B2 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-08 US disclosed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 ALDH1A1 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.