Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383949 | 0.86 | CYP2D6 (0.39) | KDM4EALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL5390237 | 0.79 | RORC (0.34) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL22946201 | 0.76 | HCRTR1 (0.57) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5182745 | 0.74 | RORC (0.33) | ALDH1A1LMNARORC | |
| SCHEMBL3190994 | 0.72 | PTGS2 (0.37) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4514603 | 0.72 | CYP1A2 (0.53) | PDE3BPDE3AKDM4EATMALDH1A1 | |
| SCHEMBL6803024 | 0.71 | MEN1 (0.46) | KMT2AMEN1 | |
| SCHEMBL6803018 | 0.71 | MEN1 (0.46) | KMT2AMEN1 | |
| SCHEMBL5393876 | 0.71 | KDM4E (0.31) | KDM4EALDH1A1LMNARORCHTT | |
| SCHEMBL9079083 | 0.71 | ABL1 (0.42) | PDE3BPDE3AKDM4EATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-03-10 | — | — | US | disclosed |
| US-6825183-B2 | CONTROLLING PLANTS; ANTIGROWTH AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | DDT, CYP1B1, CYP1A1 | PDE3B 3866/4885PDE3A 3253/4885KDM4E 1760/4885 |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | DDT, CYP1B1, CYP1A1 | PDE3B 3062/4885PDE3A 2578/4885KDM4E 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.