Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380259 | 0.86 | PDE3B (0.37) | CYP2D6CYP2C19CYP1A2CYP3A4LMNA | |
| SCHEMBL5390237 | 0.82 | RORC (0.34) | CYP2D6CYP2C19CYP1A2CYP3A4LMNA | |
| SCHEMBL5182745 | 0.77 | RORC (0.33) | LMNAALDH1A1RORCTSHR | |
| SCHEMBL4861237 | 0.75 | GABRP (0.38) | CYP2D6CYP2C19CYP1A2CYP3A4LMNA | |
| SCHEMBL5393876 | 0.74 | KDM4E (0.31) | LMNAKDM4EALDH1A1RORC | |
| SCHEMBL30423757 | 0.72 | CYP2A13 (0.58) | KMT2AMEN1ALDH1A1HPGDRORC | |
| SCHEMBL22946195 | 0.72 | CYP2A13 (0.58) | KMT2AMEN1ALDH1A1HPGDRORC | |
| SCHEMBL10397526 | 0.70 | TSHR (0.47) | CYP1A2LMNAKMT2APOLBKDM4E | |
| SCHEMBL2905106 | 0.69 | CLCN2 (0.38) | CYP2D6CYP2C19CYP1A2CYP3A4LMNA | |
| SCHEMBL8924899 | 0.69 | DRD3 (0.60) | CYP2D6CYP1A2LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-03-10 | — | — | US | disclosed |
| US-6825183-B2 | CONTROLLING PLANTS; ANTIGROWTH AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| EP-1244634-B1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-26 | — | — | US | disclosed |
| EP-1244634-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047894-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | DDT, CYP1B1, CYP1A1 | CYP2D6 30/4885CYP2C19 314/4885CYP1A2 7/4885 |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | DDT, CYP1B1, CYP1A1 | CYP2D6 37/4885CYP2C19 311/4885CYP1A2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.