Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169866 | 0.87 | HCAR1 (0.61) | TPMTHCAR1HPGDALDH1A1NPC1 | |
| SCHEMBL28709440 | 0.78 | TPMT (0.52) | TPMTHCAR1PRSS1PRSS2C1S | |
| SCHEMBL775679 | 0.78 | PARP1 (0.59) | HPGDNPC1RAB9ASMN1; SMN2PARP1 | |
| SCHEMBL775142 | 0.75 | ALDH1A1 (0.56) | HPGDALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL28709441 | 0.73 | TPMT (0.46) | TPMTHCAR1PRSS1PRSS2C1S | |
| SCHEMBL28709442 | 0.73 | TPMT (0.46) | TPMTHCAR1PRSS1PRSS2C1S | |
| SCHEMBL16305559 | 0.73 | TPMT (0.65) | TPMTHCAR1PRSS1PRSS2C1S | |
| SCHEMBL7937175 | 0.73 | TPMT (0.65) | TPMTHCAR1PRSS1PRSS2C1S | |
| SCHEMBL31054325 | 0.72 | MAPT (0.65) | TPMTHPGDALDH1A1NPSR1NPC1 | |
| SCHEMBL133987 | 0.70 | TPMT (0.62) | TPMTHCAR1PRSS1PRSS2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126591-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-7205428-B2 | Thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2007-04-17 | — | — | US | disclosed |
| EP-1219667-B1 | Novel thioether derivatives, their method for production and use | COMM RES LAB INDEPENDENT ADMIN (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-6630578-B2 | Which respond immediately by emission of light when stimulated with light or electric energy, and are useful as switching material of memory | COMMUNICATIONS RESEARCH LABORATORY, INDEPENDENT ADMINISTRATIVE INSTITUTION (JP) | 2003-10-07 | — | — | US | disclosed |
| US-20030171507-A1 | Novel thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1219667-A2 | Novel thioether derivatives, their method for production and use | Communications Research Laboratory, Independent Administrative Institution (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020072583-A1 | Novel thioether derivatives, their method for production and use | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) | 2002-06-13 | — | — | US | disclosed |