Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133987 | 0.97 | TPMT (0.62) | TPMTALDH1A1LMNAHCAR1PRSS1 | |
| SCHEMBL11947078 | 0.92 | LMNA (0.67) | TPMTALDH1A1LMNAHPGDRXRA | |
| SCHEMBL12792084 | 0.87 | ALDH1A1 (0.76) | TPMTALDH1A1LMNAHPGDRXRA | |
| SCHEMBL7194390 | 0.87 | ALDH1A1 (0.57) | TPMTALDH1A1LMNAHCAR1PRSS1 | |
| SCHEMBL21887693 | 0.87 | TPMT (0.81) | TPMTALDH1A1LMNAHCAR1HPGD | |
| SCHEMBL12409035 | 0.87 | ALDH1A1 (0.76) | TPMTALDH1A1LMNAHPGDRXRA | |
| SCHEMBL14286947 | 0.85 | ALDH1A1 (0.64) | TPMTALDH1A1LMNAHPGDSRD5A2 | |
| SCHEMBL11609313 | 0.84 | TPMT (0.54) | TPMTALDH1A1LMNAHCAR1PRSS1 | |
| SCHEMBL134238 | 0.84 | RXRA (0.54) | TPMTALDH1A1LMNAHCAR1PRSS1 | |
| SCHEMBL11615210 | 0.83 | PARP1 (0.61) | LMNAHPGDPARP1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057559-A | Preparation method of diaryl ketone | 中南民族大学 | 2022-02-18 | — | — | CN | disclosed |
| US-9636670-B2 | Catalysts, ligands and use thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-02 | — | — | US | disclosed |
| US-9636670-B2 | Catalysts, ligands and use thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-02 | — | — | US | disclosed |
| US-9636670-B2 | Catalysts, ligands and use thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-02 | — | — | US | disclosed |
| US-20160093812-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | US | disclosed |
| US-20160074852-A1 | CATALYSTS, LIGANDS AND USE THEREOF | ISIS INNOVATION LIMITED (GB) | 2016-03-17 | — | — | US | disclosed |
| US-20160074852-A1 | CATALYSTS, LIGANDS AND USE THEREOF | ISIS INNOVATION LIMITED (GB) | 2016-03-17 | — | — | US | disclosed |
| US-9278488-B2 | Polyamic acid polymer composite and preparation method thereof | LG CHEM, LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| EP-2986375-A2 | CATALYSTS, LIGANDS AND USE THEREOF | Isis Innovation Limited (GB) | 2016-02-24 | — | — | EP | disclosed |
| US-20140316074-A1 | POLYAMIC ACID POLYMER COMPOSITE AND PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2014-10-23 | — | — | US | disclosed |
| EP-0986557-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0986557-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0986550-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055479-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |
| WO-1998055470-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |
| US-5110940-A | Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase | BRISTOL-MYERS COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| US-4897490-A | DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE | BRISTOL-MEYERS COMPANY (US) | 1990-01-30 | — | — | US | disclosed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |
| US-4042587-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074852-A1 | CATALYSTS, LIGANDS AND USE THEREOF | SPR, SQOR, COASY | TPMT 1691/4885ALDH1A1 1077/4885LMNA 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.