Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380440 | 1.00 | OGG1 (0.42) | OGG1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL5284909 | 0.77 | MAPT (0.47) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5284896 | 0.77 | MAPT (0.47) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5282916 | 0.69 | NPC1 (0.38) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5282918 | 0.69 | NPC1 (0.38) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5278396 | 0.64 | MAPT (0.64) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5278390 | 0.64 | MAPT (0.64) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL15516973 | 0.63 | ALDH1A1 (0.63) | OGG1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL11874801 | 0.62 | HSD17B10 (0.71) | OGG1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL11869994 | 0.62 | NOTUM (0.67) | OGG1NPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294151-B2 | Means and method for dyeing keratin fibres | WELLA AG (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KOYO SEIKO CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KRT18, KLK5, KIT | OGG1 1066/4885NPC1 4843/4885RAB9A 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.