SCHEMBL5380467

SCHEMBL5380467

Oc1ccc(-c2ccccc2Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.65
USP7 Q93009 2/20 0.62
ABL1 P00519 2/20 0.56
ABCB1 P08183 2/20 0.56
BCR P11274 2/20 0.56
MAOB P27338 2/20 0.52
ESR2 Q92731 4/20 0.50
DEGS1 O15121 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
ESR1 P03372 4/20 0.46
SCN9A Q15858 1/20 0.45
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27256946 0.88 CYP2A6 (0.77) CYP2A6USP7ABL1ABCB1BCR
SCHEMBL20961502 0.83 ABL1 (0.53) CYP2A6USP7ABL1ABCB1BCR
SCHEMBL1513559 0.82 CNR2 (0.50) CYP2A6USP7ABL1ABCB1BCR
SCHEMBL4432976 0.82 ABL1 (0.76) ABL1ABCB1BCRESR2MMP3
SCHEMBL1649339 0.82 ABL1 (0.76) ABL1ABCB1BCRESR2MMP3
SCHEMBL20961248 0.81 ABL1 (0.52) CYP2A6USP7ABL1ABCB1BCR
SCHEMBL29291169 0.80 CYP2A6 (0.54) CYP2A6USP7ABL1ABCB1BCR
SCHEMBL6436152 0.80 CYP2A6 (0.90) CYP2A6USP7MAOBESR2BCL2L1
SCHEMBL671819 0.80 CYP2A6 (0.71) CYP2A6USP7MAOBSCN9AALDH1A1
SCHEMBL29453518 0.80 CYP2A6 (0.71) CYP2A6USP7MAOBSCN9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108239027-A The synthetic method of pharmaceutical intermediate 1- methyl -2- quinolinones 成都卡迪夫科技有限公司 2018-07-03 CN claimed
US-9161542-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2015-10-20 US claimed
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 US claimed
WO-2012162595-A2 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 WO claimed
US-20010046688-A1 Novel stabilized formulations for chemiluminescent assays GIRI BRIJ PAL (US) 2001-11-29 US claimed
CN-1030139-A A kind of new method of immunity UNILEVER NV (NL) 1989-01-04 CN claimed
CN-116600801-A HSD17B13 inhibitors and uses thereof FL2022-001公司 2023-08-15 CN disclosed
CN-113461504-B Method for preparing macrocyclic ketone from epoxide 中国天辰工程有限公司 2023-04-21 CN disclosed
CN-113461504-A Method for preparing macrocyclic alkanone from epoxide 中国天辰工程有限公司 2021-10-01 CN disclosed
CN-110227463-A A kind of novel fenton catalyst and preparation method thereof for degradable organic pollutant waste water 浙江工业大学 2019-09-13 CN disclosed
CN-108250177-B A kind of preparation method of 1,4- benzdioxan -2- formic acid 上海馨远医药科技有限公司 2019-05-17 CN disclosed
CN-109647443-A The embedding graphene nanometer sheet of coralliform copper-molybdenum sulphur microsphere and its synthetic method and purposes 广州大学 2019-04-19 CN disclosed
CN-108793377-A One Yeasts load the preparation method of Nanoscale Iron metal/composite material 湖南农业大学 2018-11-13 CN disclosed
EP-0273693-A1 Method for production of catalyst component for olefin polymerization Tonen Corporation (JP) 1988-07-06 EP disclosed
EP-0273695-A1 Method of production of catalyst carrier for polymerization of olefin Tonen Corporation (JP) 1988-07-06 EP disclosed
EP-0273694-A1 Method for production of catalyst component for olefin polymerization Tonen Corporation (JP) 1988-07-06 EP disclosed
EP-0272099-A2 Color-forming sheet recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-06-22 EP disclosed
US-4705843-A Process for the production of substituted polyaryl ethers BAYER AKTIENGESELLSCHAFT (DE) 1987-11-10 US disclosed
EP-0161484-A1 Essentially ortho-linked poly(aryl ethers) BAYER AG (DE) 1985-11-21 EP disclosed
US-4290905-A FOR LIQUID CRYSTAL DISPLAYS KABUSHIKI KAISHA SUWA SEIKOSHA (JP) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS PRDX6, PRDX2, PRDX1 CYP2A6 1649/4885USP7 947/4885ABL1 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.