SCHEMBL671819

SCHEMBL671819

Clc1ccc(-c2ccccc2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.71
TSHR P16473 2/20 0.57
NPC1 O15118 2/20 0.57
TP53 P04637 2/20 0.57
RAB9A P51151 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
NFKB1 P19838 1/20 0.57
CASP3 P42574 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57
SENP8 Q96LD8 1/20 0.57
HSD17B10 Q99714 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
MAOB P27338 2/20 0.55
CYP1A2 P05177 1/20 0.55
PTGS2 P35354 2/20 0.50
PTGS1 P23219 1/20 0.50
AHR P35869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29453518 1.00 CYP2A6 (0.71) CYP2A6TSHRNPC1TP53RAB9A
Methane SCHEMBL27895599 0.97 CYP2A6 (0.68) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL22322516 0.93 CYP2A6 (0.62) CYP2A6TSHRNPC1TP53RAB9A
Methylene Chloride SCHEMBL28774807 0.93 CYP2A6 (0.62) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL7124649 0.93 CYP2A6 (0.77) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL9863007 0.90 CYP2A6 (0.58) CYP2A6TSHRNPC1TP53RAB9A
Trichloroethane SCHEMBL28457430 0.89 CYP2A6 (0.58) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL9862848 0.86 CYP1A2 (0.63) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL6436152 0.84 CYP2A6 (0.90) CYP2A6TSHRNPC1TP53RAB9A
SCHEMBL23628571 0.83 CYP2A6 (1.00) CYP2A6TSHRNPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1031 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115372493-A Method for detecting 24 pesticide residues in traditional Chinese medicine and application 广东微谱检测技术有限公司 2022-11-22 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-112694617-A Modified silicone oil, surfactant, preparation method and application thereof 南京美思德新材料有限公司 2021-04-23 CN claimed
US-8975367-B2 Polyphosphonate and copolyphosphonate additive mixtures FRX POLYMERS, INC. (US) 2015-03-10 US claimed
EP-2697309-A2 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX Polymers, Inc. (US) 2014-02-19 EP claimed
US-20120264844-A1 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 US claimed
WO-2012142596-A2 POLYPHOSPHONATE AND COPOLYPHOSPHONATE ADDITIVE MIXTURES FRX POLYMERS, INC. (US) 2012-10-18 WO claimed
US-7989194-B2 PCB-degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2011-08-02 US claimed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP claimed
US-20080318302-A1 PCB-Degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2008-12-25 US claimed
EP-1005881-B1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KK (JP) 2005-01-19 EP claimed
US-6616815-B2 Contacting under irradiation with light a medium containing at least one of a halogenated aliphatic hydrocarbon compound and an aromatic compound with functional water produced by electrolysis of water containing an electrolyte CANON KABUSHIKI KAISHA (JP) 2003-09-09 US claimed
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2003-09-04 US claimed
US-20030148501-A1 Compositions and methods useful in bioremediation of polychlorinated biphenyls NATIONAL SCIENCE FOUNDATION 2003-08-07 US claimed
US-6537797-B1 Isolated bacterium that utilizes 2,3-dichloro-biphenyl as a sole carbon source INDIANA UNIVERSITY, ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE 2003-03-25 US claimed
US-20020163135-A1 METHOD FOR DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS, METHOD FOR CLEANING MEDIUM CONTAMINATED WITH AT LEAST ONE OF THESE COMPOUNDS, AND APPARATUS FOR THESE CANON KABUSHIKI KAISHA (JP) 2002-11-07 US claimed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds AHR, ARNT, TRPA1 CYP2A6 1561/4885TSHR 1991/4885NPC1 3588/4885
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME AHR, ARNT, TRPA1 CYP2A6 1162/4885TSHR 1532/4885NPC1 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.