Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 16/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 16/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 16/20 | 0.60 |
| ▸ | RAF1 | P04049 | 12/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | GCGR | P47871 | 4/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383500 | 0.82 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5390319 | 0.82 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5382372 | 0.81 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5380270 | 0.80 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5390448 | 0.79 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5381409 | 0.77 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5380497 | 0.76 | POLB (0.85) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL7228717 | 0.76 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL2949385 | 0.76 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL11516210 | 0.75 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |