Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.70 |
| ▸ | IDO1 | P14902 | 7/20 | 0.64 |
| ▸ | TDO2 | P48775 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998981 | 0.91 | EGFR (0.72) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL1302976 | 0.83 | EGFR (0.69) | EGFRIDO1TDO2GSK3BMAPT | |
| SCHEMBL29437202 | 0.83 | EGFR (0.69) | EGFRIDO1TDO2GSK3BMAPT | |
| SCHEMBL1388746 | 0.83 | EGFR (1.00) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL320134 | 0.82 | IDO1 (0.57) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL397709 | 0.81 | IDO1 (0.70) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL24811418 | 0.81 | EGFR (0.51) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL24811063 | 0.81 | EGFR (0.51) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL10789931 | 0.81 | IDO1 (0.69) | EGFRIDO1TDO2GSK3BSRC | |
| SCHEMBL8999062 | 0.80 | MAPT (0.56) | EGFRIDO1TDO2GSK3BSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731648-B1 | FLAVOURING COMPOSITIONS AND METHOD | FIRMENICH & CIE (CH) | 2003-03-26 | — | — | EP | claimed |
| JP-2002542797-A | — | — | 2002-12-17 | — | — | JP | claimed |
| US-6403144-B1 | LECITHIN ANTISTICK AGENT, NUCLEOTIDE FLAVOR ENHANCER, POLYDIMETHYLSILOXANE ANTIFOAM AGENT, RELATIVELY LOW AMOUNTS YET PROVIDE IMPROVED FLAVOR, TEXTURE AND AROMA OF COOKING OIL, COOKING SPRAY, AND SHORTENING | THE PROCTER & GAMBLE CO. | 2002-06-11 | — | — | US | claimed |
| US-20020045001-A1 | Food preparation compositions | THE J.M. SMUCKER COMPANY | 2002-04-18 | — | — | US | claimed |
| EP-1176879-A1 | FOOD PREPARATION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000065933-A1 | FOOD PREPARATION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-09 | — | — | WO | claimed |
| EP-3806661-B1 | USE OF ANTAGONISTS OF T2R54 | FIRMENICH INCORPORATED (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4566459-A2 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | Firmenich Incorporated (US) | 2025-06-11 | — | — | EP | disclosed |
| US-12295396-B2 | Antagonists of T2R54 and compositions and uses thereof | FIRMENICH INCORPORATED (US) | 2025-05-13 | — | — | US | disclosed |
| CN-113194742-B | Antagonists of T2R54, compositions thereof and uses thereof | 弗门尼舍公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20240114942-A1 | Antagonists of T2R54 and Compositions and Uses Thereof | FIRMENICH INCORPORATED (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11871772-B2 | Antagonists of T2R54 and compositions and uses thereof | FIRMENICH INCORPORATED (US) | 2024-01-16 | — | — | US | disclosed |
| US-6287620-B1 | Flavor enhancing methods | FIRMENICH SA (CH) | 2001-09-11 | — | — | US | disclosed |
| WO-2000065933-A1 | FOOD PREPARATION COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000065926-A1 | FLAVOR ENHANCING OILS | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-09 | — | — | WO | disclosed |
| EP-0731648-A1 | FLAVOURING COMPOSITIONS AND METHOD | FIRMENICH SA (CH) | 1996-09-18 | — | — | EP | disclosed |
| WO-1996010927-A1 | FLAVOURING COMPOSITIONS AND METHOD | FIRMENICH S.A. (CH) | 1996-04-18 | — | — | WO | disclosed |
| EP-0654024-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003427-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | EGFR 4124/4885IDO1 4526/4885TDO2 4292/4885 |
| US-11871772-B2 | Antagonists of T2R54 and compositions and uses thereof | TAS2R50, TAS2R30, TAS2R60 | EGFR 431/4885IDO1 2597/4885TDO2 1991/4885 |
| US-12295396-B2 | Antagonists of T2R54 and compositions and uses thereof | TAS2R50, TAS2R30, TAS2R60 | EGFR 431/4885IDO1 2597/4885TDO2 1991/4885 |
| US-20240114942-A1 | Antagonists of T2R54 and Compositions and Uses Thereof | TAS2R50, TAS2R30, TAS2R60 | EGFR 431/4885IDO1 2597/4885TDO2 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.