SCHEMBL5381473

SCHEMBL5381473

CCOC(=O)c1cccc(CC(O)CO)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 3/20 0.50
TSHR P16473 1/20 0.49
CDC25B P30305 4/20 0.41
MAPT P10636 4/20 0.41
ALOX15 P16050 3/20 0.41
HPGD P15428 3/20 0.41
GAA P10253 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CYP1A2 P05177 3/20 0.39
LMNA P02545 3/20 0.39
CYP3A4 P08684 2/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28109417 0.86 TSHR (0.59) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL27493209 0.83 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL3458043 0.82 ALDH1A1 (0.62) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL2302249 0.80 G6PD (0.47) ALDH1A1TSHRMAPTALOX15LMNA
SCHEMBL28140336 0.80 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL27424975 0.79 TSHR (0.70) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL28280208 0.79 ALDH1A1 (0.57) ALDH1A1HSD17B10TSHRCDC25BMAPT
SCHEMBL1443561 0.78 LMNA (0.45) ALDH1A1HSD17B10TSHRMAPTALOX15
SCHEMBL27743439 0.78 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRCDC25BMAPT
Diethyl Phthalate SCHEMBL15741420 0.78 TSHR (0.75) ALDH1A1HSD17B10TSHRCDC25BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107260561-A Cosmetic and/or dermatological composition containing merocyanine derivatives 莱雅公司 2017-10-20 CN disclosed
CN-103917218-B Cosmetic and/or dermatological compositions containing merocyanine derivatives comprising specific polar groups constituted by hydroxyl-and ether-functional groups 莱雅公司 2017-06-09 CN disclosed
CN-101090630-A Formulations containing insect repellent compounds DU PONT (US) 2007-12-19 CN disclosed
US-7309481-B2 Natural sunlight photostable composition TANNING RESEARCH LABORATORIES, INC. (US) 2007-12-18 US disclosed
US-7285262-B2 Natural sunlight photostable composition TANNING RESEARCH LABORATORIES, INC. (US) 2007-10-23 US disclosed
WO-2006086354-A2 NATURAL SUNLIGHT PHOTOSTABLE COMPOSITION TANNING RESEARCH LABORATORIES, INC. (US) 2006-08-17 WO disclosed
US-20060177389-A1 Natural sunlight photostable composition EVEREADY BATTERY COMPANY, LLC 2006-08-10 US disclosed
WO-2006016975-A2 NATURAL SUNLIGHT PHOTOSTABLE COMPOSITION TANNING RESEARCH LABORATORIES, INC. (US) 2006-02-16 WO disclosed
US-20050025727-A1 Combination of avobenzone, octocrylene and oxybenzone; minimizes formation of harmful free radicals EVEREADY BATTERY COMPANY, LLC 2005-02-03 US disclosed