SCHEMBL538221

SCHEMBL538221

C=C(C)COc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.51
ABCB1 P08183 7/20 0.51
DRD2 P14416 1/20 0.51
DRD1 P21728 1/20 0.51
DRD3 P35462 1/20 0.51
PTGDR2 Q9Y5Y4 2/20 0.50
POLB P06746 1/20 0.48
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 1/20 0.44
AKR1C3 P42330 1/20 0.44
GPR174 Q9BXC1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10892150 0.88 ELANE (0.43) ELANEABCB1DRD2DRD1DRD3
SCHEMBL3316012 0.85 KDM4E (0.65) POLBKDM4EHTTMAPTMEN1
SCHEMBL16966571 0.85 KDM4E (0.65) POLBKDM4EHTTMAPTMEN1
SCHEMBL11058652 0.84 PTGDR2 (0.54) ABCB1PTGDR2POLBMEN1KMT2A
SCHEMBL3314748 0.84 KDM4E (0.63) POLBKDM4EHTTMAPTMEN1
SCHEMBL867129 0.83 PTGDR2 (0.68) ELANEABCB1DRD2DRD1DRD3
SCHEMBL29388652 0.83 PTGDR2 (0.68) ELANEABCB1DRD2DRD1DRD3
SCHEMBL11056067 0.83 POLB (0.71) ELANEPTGDR2POLBKDM4EHTT
SCHEMBL6928774 0.82 ABCB1 (0.49) ELANEABCB1DRD2DRD1DRD3
SCHEMBL14092915 0.82 KDM4E (0.46) ABCB1POLBKDM4EHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114127216-B Pressure-sensitive adhesive sheet and use thereof 日东电工株式会社 2025-02-25 CN disclosed
US-12215258-B2 Pressure-sensitive adhesive sheet and use thereof NITTO DENKO CORPORATION (JP) 2025-02-04 US disclosed
CN-113412317-B Pressure-sensitive adhesive sheet 日东电工株式会社 2023-11-28 CN disclosed
US-20230002409-A1 MACROCYCLIC FLU ENDONUCLEASE INHIBITORS JANSSEN BIOPHARMA INC (US) 2023-01-05 US disclosed
US-20230002409-A1 MACROCYCLIC FLU ENDONUCLEASE INHIBITORS JANSSEN BIOPHARMA INC (US) 2023-01-05 US disclosed
US-20220275254-A1 PRESSURE-SENSITIVE ADHESIVE SHEET AND USE THEREOF NITTO DENKO CORPORATION (JP) 2022-09-01 US disclosed
US-20220195256-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2022-06-23 US disclosed
US-11312727-B1 Macrocyclic flu endonuclease inhibitors Janssen Biopharma, Inc. (US) 2022-04-26 US disclosed
US-11312727-B1 Macrocyclic flu endonuclease inhibitors Janssen Biopharma, Inc. (US) 2022-04-26 US disclosed
US-20220119685-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2022-04-21 US disclosed
EP-2277965-A2 Removable pressure-sensitive adhesive composition and pressure-sensitive adhesive tape or sheet Nitto Denko Corporation (JP) 2011-01-26 EP disclosed
WO-2010112474-A1 COATING COMPOSITION, (METH)ACRYL-POLYMER AND MONOMER MIXTURE FOR PRODUCING SAID (METH)ACRYL-POLYMER EVONIK RÖHM GMBH (DE) 2010-10-07 WO disclosed
US-20080138618-A1 REMOVABLE PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE OR SHEET NITTO DENKO CORPORATION (JP) 2008-06-12 US disclosed
EP-1930386-A2 Removable pressure-sensitive adhesive composition and pressure-sensitive adhesive tape or sheet NITTO DENKO CORPORATION (JP) 2008-06-11 EP disclosed
EP-0367054-B1 UV CROSSLINKABLE COMPOSITION BASED ON COPOLYMERS OF ISOAMYL (METH)ACRYLATES BASF Aktiengesellschaft (DE) 1993-06-23 EP disclosed
US-5026806-A Hot melt adhesives BASF AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0367054-A2 UV crosslinkable composition based on copolymers of isoamyl (meth)acrylates BASF Aktiengesellschaft (DE) 1990-05-09 EP disclosed
EP-0088842-B1 ORGANOPOLYSILOXANE PHOTOSENSITIZERS AND METHODS FOR THEIR PREPARATION Toray Silicone Company Limited (JP) 1986-01-02 EP disclosed
US-4467082-A Organopolysiloxane photosensitizers and methods for their preparation DOW CORNING CORPORATION (US) 1984-08-21 US disclosed
EP-0088842-A1 Organopolysiloxane photosensitizers and methods for their preparation Toray Silicone Company Limited (JP) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002409-A1 MACROCYCLIC FLU ENDONUCLEASE INHIBITORS ACE, PNP, FEN1 ELANE 481/4885ABCB1 800/4885DRD2 4555/4885
US-11312727-B1 Macrocyclic flu endonuclease inhibitors ACE, FEN1, PNP ELANE 382/4885ABCB1 794/4885DRD2 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.