Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538221 | 0.82 | ELANE (0.51) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL29388652 | 0.81 | PTGDR2 (0.68) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL867129 | 0.81 | PTGDR2 (0.68) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL22209162 | 0.78 | HTT (0.73) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL720460 | 0.78 | RAB9A (0.67) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL30033997 | 0.78 | RAB9A (0.67) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL21549816 | 0.78 | DRD2 (0.57) | ABCB1DRD2DRD1DRD3ELANE | |
| Bicarbonate SCHEMBL27740096 | 0.76 | RAB9A (0.65) | ABCB1DRD2DRD1DRD3ELANE | |
| Hydrochloric Acid SCHEMBL8729799 | 0.76 | RAB9A (0.65) | ABCB1DRD2DRD1DRD3ELANE | |
| SCHEMBL30149165 | 0.76 | DRD2 (0.57) | ABCB1DRD2DRD1DRD3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |