Fluorescein

Fluorescein

SCHEMBL538249

N.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.97
MAPT P10636 4/20 0.97
MEN1 O00255 4/20 0.97
KMT2A Q03164 4/20 0.97
TDP1 Q9NUW8 3/20 0.97
HTT P42858 2/20 0.97
HPGD P15428 2/20 0.97
RECQL P46063 2/20 0.97
BLM P54132 2/20 0.97
PRMT1 Q99873 2/20 0.97
ACE2 Q9BYF1 2/20 0.97
CYP2C19 P33261 1/20 0.97
SMAD3 P84022 1/20 0.97
LMNA P02545 3/20 0.68
GPR55 Q9Y2T6 2/20 0.68
ALOX12 P18054 2/20 0.68
POLB P06746 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
ALDH1A1 P00352 3/20 0.61
USP2 O75604 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL8144835 1.00 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL6691088 0.99 FTO (0.94) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3645090 0.98 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29388667 0.98 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 0.98 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL16533 0.98 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL30272223 0.98 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL4167675 0.97 FTO (0.92) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL17867543 0.97 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL21194999 0.97 FTO (0.97) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115825018-A Fluorescent biological polysaccharide for nano pesticide in-situ fluorescence detection and detection method thereof 中山大学 2023-03-21 CN claimed
US-20210275693-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. 2021-09-09 US claimed
CN-112055595-A Methods of use of CAR T cells 恩多塞特公司 2020-12-08 CN claimed
US-10781442-B2 High-speed in vitro screening method EPSILON MOLECULAR ENGINEERING INC. (JP) 2020-09-22 US claimed
US-20190307904-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC (US) 2019-10-10 US claimed
US-20190085322-A1 HIGH-SPEED IN VITRO SCREENING METHOD EPSILON MOLECULAR ENGINEERING INC. (JP) 2019-03-21 US claimed
EP-3436012-A1 MODIFIED WOUND DRESSINGS ConvaTec Technologies Inc. (US) 2019-02-06 EP claimed
CN-109219436-A modified wound dressing 康沃特克科技公司 2019-01-15 CN claimed
CN-107421863-A It is a kind of to combine the PM that monodisperse aerosol occurs1Cutting head Performance Test System 北京航空航天大学 2017-12-01 CN claimed
WO-2017173026-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. (US) 2017-10-05 WO claimed
EP-0708767-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1996-05-01 EP claimed
EP-0702689-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LABORATORIES (US) 1996-03-27 EP claimed
US-5424414-A Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids ABBOTT LABORATORIES (US) 1995-06-13 US claimed
WO-1995003296-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1995-02-02 WO claimed
WO-1994029329-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LABORATORIES (US) 1994-12-22 WO claimed
WO-1993020074-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR ACRIDINE-9-CARBOXYLIC ACIDS ABBOTT LABORATORIES (US) 1993-10-14 WO claimed
WO-1993020094-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR QUINOLINE ABBOTT LABORATORIES (US) 1993-10-14 WO claimed
US-5145790-A Immunoassay, fluorescein derivative ABBOTT LABORATORIES (US) 1992-09-08 US claimed
EP-0455058-A2 Reagents and method for detecting polychlorinated biphenyls ABBOTT LABORATORIES (US) 1991-11-06 EP claimed
US-4171311-A Imides of thyroxin and triiodothyronine International Diagnostics Tech. Inc. (US) 1979-10-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190307904-A1 MODIFIED WOUND DRESSINGS MMP8, CD68, ELANE FTO 850/4885MAPT 4774/4885MEN1 4751/4885
US-20210275693-A1 MODIFIED WOUND DRESSINGS MMP8, CD68, ELANE FTO 850/4885MAPT 4774/4885MEN1 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.