Acetamide

Acetamide

SCHEMBL538407

CC(N)=O.Cc1ccc(S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.73
PKM P14618 4/20 0.63
ALDH1A1 P00352 3/20 0.59
MAPT P10636 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
CA2 P00918 4/20 0.54
CA1 P00915 2/20 0.54
CA12 O43570 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
F2 P00734 3/20 0.53
PRSS1 P07477 3/20 0.53
PRSS2 P07478 3/20 0.53
PRSS3 P35030 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL11593292 0.85 GAA (0.89) GAAPKMALDH1A1MAPTMEN1
SCHEMBL4400955 0.85 GAA (1.00) GAAPKMALDH1A1MAPTMEN1
SCHEMBL10067072 0.85 GAA (1.00) GAAPKMALDH1A1MAPTMEN1
SCHEMBL170033 0.85 GAA (1.00) GAAPKMALDH1A1MAPTMEN1
Acetamide SCHEMBL5102677 0.84 ALDH1A1 (0.55) GAAPKMALDH1A1MAPTCA2
Water SCHEMBL9619041 0.83 GAA (0.94) GAAPKMALDH1A1MAPTMEN1
SCHEMBL3773485 0.83 GAA (0.67) GAAPKMALDH1A1MAPTMEN1
P-Xylene SCHEMBL10441943 0.83 ALDH1A1 (0.55) GAAPKMALDH1A1MAPTMEN1
SCHEMBL8623342 0.82 GAA (0.59) GAAPKMALDH1A1MAPTMEN1
SCHEMBL8558497 0.79 GAA (0.61) GAAPKMALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8232031-B2 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same RICOH COMPANY, LTD. (JP) 2012-07-31 US disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
EP-2146251-B1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH CO LTD (JP) 2012-02-08 EP disclosed
WO-2011071674-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-06-16 WO disclosed
EP-2033961-B1 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same RICOH CO LTD (JP) 2011-03-23 EP disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
EP-2146251-A1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge Ricoh Company, Ltd. (JP) 2010-01-20 EP disclosed
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME RICOH COMPANY, LTD. (JP) 2009-03-12 US disclosed
EP-2033961-A1 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same Ricoh Company, Ltd. (JP) 2009-03-11 EP disclosed
US-7139512-B2 Charging device, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2006-11-21 US disclosed
US-20060062598-A1 Charging device, process cartridge and image forming apparatus NAMIKI AKIYO 2006-03-23 US disclosed
US-20040072045-A1 Proton-conductive polymer film and process for producing the same KANEKA CORPORATION (JP) 2004-04-15 US disclosed
EP-1380619-A1 PROTON-CONDUCTIVE POLYMER FILM AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2004-01-14 EP disclosed
US-6670002-B1 Sheet which comprises support bearing ink-receiving layer comprising pigment and/or colloidal particles and binder resin and containing anti-yellowing effective amount of at least one organic titanium compound MITSUBISHI PAPER MILLS LIMITED (JP) 2003-12-30 US disclosed
US-20030175046-A1 Charging device, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2003-09-18 US disclosed
US-6485812-B1 Ink jet recording sheet and process for producing it MITSUBISHI PAPER MILLS LIMITED (JP) 2002-11-26 US disclosed
US-6354207-B1 Solid ink printing master plate and method for preparing the same HITACHI KOKI CO., LTD. (JP) 2002-03-12 US disclosed
US-5439773-A Electrically-conductive toner, process for preparation of same, and process for formation of image using same FUJI XEROX CO., LTD. (JP) 1995-08-08 US disclosed
US-5407770-A Capsule toner and process for producing the same FUJI XEROX CO., LTD. (JP) 1995-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME PAH, AHR, DECR1 GAA 4528/4885PKM 2937/4885ALDH1A1 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.