SCHEMBL8623342

SCHEMBL8623342

CC(=O)OS(=O)(=O)c1ccc(S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
PKM P14618 3/20 0.54
MAPT P10636 3/20 0.52
POLB P06746 1/20 0.52
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 3/20 0.43
RAPGEF4 Q8WZA2 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MPI P34949 1/20 0.43
MCL1 Q07820 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443434 0.94 ALDH1A1 (0.53) GAAPKMMAPTPOLBALDH1A1
SCHEMBL26088501 0.92 ALDH1A1 (0.52) GAAPKMMAPTPOLBALDH1A1
SCHEMBL10412878 0.92 ALDH1A1 (0.52) GAAPKMMAPTPOLBALDH1A1
Acetic Acid SCHEMBL10733614 0.91 ALDH1A1 (0.50) GAAPKMMAPTPOLBALDH1A1
SCHEMBL6365074 0.85 HTR6 (0.52) GAAPKMMAPTPOLBALDH1A1
Acetamide SCHEMBL538407 0.82 GAA (0.73) GAAPKMMAPTPOLBALDH1A1
SCHEMBL8618235 0.81 MAPT (0.47) GAAPKMMAPTPOLBALDH1A1
SCHEMBL10637725 0.80 ALDH1A1 (0.60) GAAPKMPOLBALDH1A1SMN1; SMN2
SCHEMBL28154895 0.79 ENPP2 (0.50) GAAPKMMAPTPOLBALDH1A1
SCHEMBL3836056 0.79 ALDH1A1 (0.58) GAAMAPTPOLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708086-B1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO LTD (JP) 1998-05-20 EP disclosed
US-5728879-A HEAT SENSITIVE ELEMENTS FOR RECORDING AND FORMING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1998-03-17 US disclosed
EP-0708086-A1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed