SCHEMBL5384235

SCHEMBL5384235

CCCCCCCCCCCCCCS(=O)(=O)CCC

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.62
FAAH O00519 5/20 0.56
CES1 P23141 5/20 0.50
CES2 O00748 2/20 0.50
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5389334 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL18643527 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL5383600 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8957776 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8778782 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8778820 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL7739945 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8778722 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8778834 1.00 CA2 (0.62) CA2FAAHCES1CES2TSHR
SCHEMBL8485736 0.97 CA2 (0.58) CA2FAAHCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US claimed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US claimed
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY 2006-04-06 US claimed
US-20060069262-A1 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY 2006-03-30 US claimed
US-6657083-B2 Photographic couplers; acylation amine group in position 2 EASTMAN KODAK COMPANY 2003-12-02 US claimed
US-6613943-B2 Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis EASTMAN KODAK COMPANY 2003-09-02 US claimed
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM EASTMAN KODAK COMPANY 2003-06-12 US claimed
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2003-06-12 US claimed
US-6525219-B1 Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation EASTMAN KODAK COMPANY 2003-02-25 US claimed
US-6476202-B1 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them EASTMAN KODAK COMPANY 2002-11-05 US claimed
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US disclosed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US disclosed
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY 2006-04-06 US disclosed
US-20060069262-A1 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY 2006-03-30 US disclosed
US-6657083-B2 Photographic couplers; acylation amine group in position 2 EASTMAN KODAK COMPANY 2003-12-02 US disclosed
EP-1316550-A1 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them EASTMAN KODAK COMPANY (US) 2003-06-04 EP disclosed
US-6525219-B1 Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation EASTMAN KODAK COMPANY 2003-02-25 US disclosed
US-6515176-B1 Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: Also disclosed is a method for forming a cyan dye-forming coupler from the above compound. The method and intermediate with a simplified EASTMAN KODAK COMPANY 2003-02-04 US disclosed
US-6482953-B1 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2002-11-19 US disclosed
US-6482985-B1 2-benzyloxy-5-halo-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2002-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them CBR3, AADAC, HAAO CA2 1033/4885FAAH 152/4885CES1 1874/4885
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM AADAT, AAAS, ANXA7 CA2 1481/4885FAAH 1756/4885CES1 4394/4885
US-20060069262-A1 Oxadiazoles and their manufacture OXA1L, CYP1B1, OXER1 CA2 4256/4885FAAH 4161/4885CES1 1501/4885
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes KCNH1, KCNJ2, KCNH2 CA2 2804/4885FAAH 1277/4885CES1 1561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.