Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817987 | 0.86 | TRPM8 (0.57) | TRPM8EPHX1RORCCYP3A4 | |
| SCHEMBL15133483 | 0.86 | TRPM8 (0.57) | TRPM8EPHX1RORCCYP3A4 | |
| SCHEMBL14664188 | 0.86 | TRPM8 (0.57) | TRPM8EPHX1RORCCYP3A4 | |
| SCHEMBL2628678 | 0.86 | TRPM8 (0.57) | TRPM8EPHX1RORCCYP3A4 | |
| SCHEMBL15133431 | 0.84 | TRPM8 (0.55) | TRPM8EPHX1TRPV1RORC | |
| SCHEMBL5391878 | 0.84 | TRPM8 (0.55) | TRPM8EPHX1TRPV1P2RX4RORC | |
| SCHEMBL2628685 | 0.84 | TRPM8 (0.55) | TRPM8EPHX1 | |
| SCHEMBL10073868 | 0.82 | TRPM8 (0.73) | TRPM8EPHX1TRPV1 | |
| SCHEMBL2761757 | 0.81 | TRPM8 (0.52) | TRPM8EPHX1TRPV1P2RX4RORC | |
| SCHEMBL4889806 | 0.81 | TRPM8 (0.57) | TRPM8EPHX1TRPV1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169377-B2 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T | 2007-01-30 | — | — | US | disclosed |
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T (US) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050084447-A1 | Radioligands for the TRP-M8 receptor and methods therewith | TRPM8, GPR68, OPRL1 | TRPM8 1/4885EPHX1 4381/4885TRPV1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.