Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25210655 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2LMNAGALR3MAPTBLM | |
| SCHEMBL2308345 | 0.73 | KMT2A (0.43) | CHRNB2CHRNA4MAPTKMT2AMEN1 | |
| SCHEMBL19072128 | 0.71 | FDPS (0.56) | LMNACHRNB2CHRNA4FDPSKMT2A | |
| SCHEMBL22468500 | 0.70 | TBXAS1 (0.48) | SMN1; SMN2LMNAFDPSKMT2AMEN1 | |
| SCHEMBL27791760 | 0.70 | RECQL (0.48) | LMNAFDPSKMT2ACYP1A2TBXAS1 | |
| SCHEMBL12240917 | 0.70 | FDPS (0.54) | LMNAFDPSKMT2ACYP1A2TBXAS1 | |
| SCHEMBL8370181 | 0.70 | FDPS (0.54) | LMNAFDPSKMT2ACYP1A2TBXAS1 | |
| SCHEMBL15455622 | 0.70 | FDPS (0.54) | LMNACHRNB2CHRNA4FDPSKMT2A | |
| SCHEMBL29780058 | 0.70 | FDPS (0.54) | LMNAFDPSKMT2ACYP1A2TBXAS1 | |
| SCHEMBL23732837 | 0.70 | TBXAS1 (0.61) | LMNACHRNB2CHRNA4FDPSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102719522-A | Application of acetylcholinesterase gene promoter in screening anti-hepatoma drugs | SHANGHAI CANCER INST | 2012-10-10 | — | — | CN | disclosed |
| US-7198942-B2 | Nucleotide sequences coding polypeptide for use in the generation of disease resistant plants and in human therapeutics | BAYER CROPSCIENCE LP (DE) | 2007-04-03 | — | — | US | disclosed |
| US-20020146765-A1 | Acetylcholine receptor subunits | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | US | disclosed |
| US-5885780-A | PREPARING OLIGONUCLEOTIDES, EACH HAVING NUCLEOTIDE SEQUENCE ENCODING A POTENTIAL CONOTOXIN-LIKE PEPTIDE WHEREIN CYS RESIDUES ARE ENCODED AT CHARACTERISTIC POSITIONS AND AMINO ACID SEQUENCES ARE CODED, INSERTING INTO VECTOR, TRANSFECTING | UNIVERSITY OF UTAH (US) | 1999-03-23 | — | — | US | disclosed |