Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374877 | 0.92 | NR1H4 (0.45) | BACE1MEN1HSP90AA1KMT2APPARG | |
| SCHEMBL5377058 | 0.90 | BACE1 (0.43) | PTGER3BACE1MEN1HSP90AA1KMT2A | |
| SCHEMBL6595113 | 0.88 | PTGER3 (0.61) | PTGER3PTGDRBACE1P2RY14ALOX5 | |
| SCHEMBL6595111 | 0.88 | PTGER3 (0.61) | PTGER3PTGDRBACE1P2RY14ALOX5 | |
| SCHEMBL5385300 | 0.82 | LTB4R (0.47) | PTGER3PTGDRBACE1PPARGP2RY14 | |
| SCHEMBL5379303 | 0.82 | ALOX5 (0.48) | PTGER3PTGDRBACE1MEN1KMT2A | |
| SCHEMBL5387806 | 0.81 | FFAR1 (0.55) | PPARGPPARA | |
| SCHEMBL6592132 | 0.80 | PTGER3 (0.51) | PTGER3PTGDRBACE1 | |
| SCHEMBL6592125 | 0.80 | PTGER3 (0.51) | PTGER3PTGDRBACE1 | |
| SCHEMBL5382479 | 0.78 | P2RY14 (0.47) | PTGER3PTGDRBACE1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |