SCHEMBL538561

SCHEMBL538561

CCOc1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.63
ESR2 Q92731 1/20 0.63
KMT2A Q03164 3/20 0.59
HCRTR1 O43613 2/20 0.55
MAPT P10636 4/20 0.55
HSD17B10 Q99714 2/20 0.54
HPGD P15428 2/20 0.54
ALOX15 P16050 1/20 0.54
ALDH1A1 P00352 4/20 0.54
TSHR P16473 1/20 0.54
L3MBTL1 Q9Y468 3/20 0.53
GLA P06280 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KDM4E B2RXH2 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MEN1 O00255 1/20 0.51
LMNA P02545 2/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL29983911 0.98 ESR1 (0.61) ESR1ESR2KMT2AHCRTR1MAPT
SCHEMBL21986971 0.94 ESR1 (0.57) ESR1ESR2KMT2AHCRTR1MAPT
SCHEMBL4392103 0.89 ESR1 (0.62) ESR1ESR2KMT2AHCRTR1MAPT
SCHEMBL4343858 0.88 ESR1 (0.51) ESR1ESR2KMT2AHCRTR1MAPT
SCHEMBL11823799 0.87 ESR1 (0.53) ESR1ESR2KMT2AHCRTR1MAPT
SCHEMBL26125296 0.87 ALDH1A1 (0.55) ESR1ESR2KMT2AMAPTHSD17B10
SCHEMBL28468927 0.87 ESR1 (0.51) ESR1ESR2KMT2AHCRTR1MAPT
Bicarbonate SCHEMBL7114860 0.86 ESR1 (0.50) ESR1ESR2KMT2AHCRTR1MAPT
Bicarbonate SCHEMBL29983692 0.86 ALDH1A1 (0.54) ESR1ESR2KMT2AMAPTHSD17B10
SCHEMBL4395023 0.86 MAPT (0.56) ESR1ESR2KMT2AMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581114-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Novozymes A/S (DK) 2025-07-09 EP claimed
US-20250163343-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORES & FRAGRANCES INC. 2025-05-22 US claimed
EP-4486857-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT International Flavors & Fragrances Inc. (US) 2025-01-08 EP claimed
US-12037461-B2 Encapped curable polyorganosiloxanes HENKEL AG & CO. KGAA (DE) 2024-07-16 US claimed
WO-2024046952-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS NOVOZYMES A/S (DK) 2024-03-07 WO claimed
WO-2023168069-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2023-09-07 WO claimed
EP-3660116-B1 ENDCAPPED CURABLE POLYORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2023-07-26 EP claimed
US-20200048578-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2020-02-13 US claimed
US-20180051231-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2018-02-22 US claimed
EP-3271443-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2018-01-24 EP claimed
WO-2008113495-A2 PERFUME COMPOSITIONS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-09-25 WO claimed
EP-1928406-A2 PHARMACEUTICAL COMPOSITIONS WITH MELTING POINT DEPRESSANT AGENTS AND METHOD OF MAKING SAME Antares Pharma IPL AG (CH) 2008-06-11 EP claimed
US-20070166341-A1 Solid volatile composition and method and system for making the same INTERNATIONAL ARTS & SCIENCE GROUP, INC. 2007-07-19 US claimed
WO-2007022924-A2 PHARMACEUTICAL COMPOSITIONS WITH MELTING POINT DEPRESSANT AGENTS AND METHOD OF MAKING SAME ANTARES PHARMA IPL AG (CH) 2007-03-01 WO claimed
US-20070048360-A1 Pharmaceutical compositions with melting point depressant agents and method of making same ANTARES PHARMA IPL AG (CH) 2007-03-01 US claimed
US-6555098-B1 Fragrance crystallites in the form of polymer surface-coated particles CHURCH & DWIGHT CO., INC. 2003-04-29 US claimed
WO-1998056337-A1 MALODOR REDUCING COMPOSITION CONTAINING AMBER AND MUSK MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1998-12-17 WO claimed
WO-1997030686-A1 COSMETIC DEODORANT PRODUCTS CONTAINING ENCAPSULATED BICARBONATE AND FRAGRANCE INGREDIENTS CHURCH & DWIGHT COMPANY, INC. (US) 1997-08-28 WO claimed
WO-1997011677-A1 COSMETIC DEODORANT PRODUCTS CONTAINING A POLYMER/FRAGRANCE-ENCAPSULATED BICARBONATE INGREDIENT CHURCH & DWIGHT COMPANY, INC. (US) 1997-04-03 WO claimed
US-5614179-A Cosmetic deodorant products containing a polymer/fragrance-encapsulated bicarbonate ingredient CHURCH & DWIGHT CO., INC. (US) 1997-03-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048360-A1 Pharmaceutical compositions with melting point depressant agents and method of making same TRPA1, TRPV1, OR51E2 ESR1 3823/4885ESR2 3404/4885KMT2A 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.