SCHEMBL4395023

SCHEMBL4395023

CCCCOc1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 2/20 0.56
MEN1 O00255 1/20 0.56
NR1I2 O75469 1/20 0.56
CHRM2 P08172 1/20 0.56
CYP3A4 P08684 1/20 0.56
ADRA2A P08913 1/20 0.56
OPRK1 P41145 1/20 0.56
HTR2B P41595 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
ALDH1A1 P00352 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
TSHR P16473 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
NPSR1 Q6W5P4 2/20 0.51
HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL29983479 0.98 MAPT (0.55) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL2169334 0.94 LMNA (0.65) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL27915224 0.94 LMNA (0.65) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL5962507 0.94 LMNA (0.65) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL2457395 0.93 LMNA (0.67) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL26125296 0.92 ALDH1A1 (0.55) MAPTKMT2ALMNAMEN1NR1I2
Bicarbonate SCHEMBL29983692 0.91 ALDH1A1 (0.54) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL11582311 0.90 LMNA (0.63) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL17530492 0.89 MAPT (0.48) MAPTKMT2ALMNAMEN1NR1I2
SCHEMBL5157734 0.89 MEN1 (0.51) MAPTKMT2ALMNAMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113025221-B Self-adhesion type polymer composite waterproof coiled material 阿尔法新材料江苏有限公司 2022-03-18 CN claimed
CN-113025221-A Self-adhesion type polymer composite waterproof coiled material 阿尔法新材料江苏有限公司 2021-06-25 CN claimed
CN-110739404-B Quantum dot light-emitting diode and preparation method thereof TCL科技集团股份有限公司 2021-04-02 CN claimed
US-4071975-A POLYISOBUTYLENE OXIDE, POLYOLEFIN; MULCHING FILM WHICH PHOTOLYTICALLY DEGRADES TO A POWDER DAICEL LTD. (JA) 1978-02-07 US claimed
US-3991138-A Resin composition for the formation of light-degradable mulching film for agricultural use DAICEL, LTD. (JA) 1976-11-09 US claimed
CN-117715650-A Extracellular vesicles derived from bacteria of the genus lactobacillus and uses thereof MD保健株式会社 2024-03-15 CN disclosed
CN-115160677-B Agricultural mulching film for high-standard farmland and preparation method thereof 甘肃宏鑫农业科技有限公司 2023-04-25 CN disclosed
EP-4014987-A2 CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE Igisu Co., Ltd. (JP) 2022-06-22 EP disclosed
US-20220183955-A1 OIL-IN-WATER EMULSION COSMETIC DOW TORAY CO., LTD. (JP) 2022-06-16 US disclosed
CN-108348361-B Absorbent structure 宝洁公司 2021-12-28 CN disclosed
US-20210330559-A1 OIL-IN-WATER EMULSION COSMETIC COMPOSITION DOW TORAY CO., LTD. (JP) 2021-10-28 US disclosed
US-20210277062-A9 CYCLIC PEPTIDE AND A MEDICAMENT, EXTERNAL PREPARATION AND COSMETIC COMPRISING SAID CYCLIC PEPTIDE IGISU CO., LTD. (JP) 2021-09-09 US disclosed
CN-100549062-C Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2009-10-14 CN disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
CN-1715306-A Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2006-01-04 CN disclosed
CN-1121376-C Substituted 4-diarylbutanoic or 5-diarylpentanoic acids and derivatives thereof as matrix metalloproteinase inhibitors BAYER AG (US) 2003-09-17 CN disclosed
CN-1163604-A Substituted 4-diarylbutanoic or 5-diarylpentanoic acids and derivatives thereof as matrix metalloproteinase inhibitors BAYER AG (US) 1997-10-29 CN disclosed
US-4071975-A POLYISOBUTYLENE OXIDE, POLYOLEFIN; MULCHING FILM WHICH PHOTOLYTICALLY DEGRADES TO A POWDER DAICEL LTD. (JA) 1978-02-07 US disclosed
US-3991138-A Resin composition for the formation of light-degradable mulching film for agricultural use DAICEL, LTD. (JA) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220183955-A1 OIL-IN-WATER EMULSION COSMETIC CUTA, LIPA, SQLE MAPT 1613/4885KMT2A 1474/4885LMNA 647/4885
US-20210277062-A9 CYCLIC PEPTIDE AND A MEDICAMENT, EXTERNAL PREPARATION AND COSMETIC COMPRISING SAID CYCLIC PEPTIDE TSLP, NPR1, VIP MAPT 3486/4885KMT2A 3255/4885LMNA 4657/4885
US-20210330559-A1 OIL-IN-WATER EMULSION COSMETIC COMPOSITION CUTA, SQLE, LIPA MAPT 1440/4885KMT2A 852/4885LMNA 314/4885
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 MAPT 1301/4885KMT2A 2526/4885LMNA 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.