SCHEMBL538608

SCHEMBL538608

Clc1cccc([Mg]Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28713663 0.98 ALDH1A1 (0.41)
SCHEMBL26122617 0.87 ALOX5 (0.47)
SCHEMBL30581258 0.87 ALOX5 (0.47)
Tetrahydrofuran SCHEMBL27861825 0.84 AKR1C3 (0.35)
SCHEMBL29579005 0.77
SCHEMBL1157014 0.77
Hydrochloric Acid SCHEMBL9453376 0.73 ALDH1A1 (0.41)
SCHEMBL2589180 0.73 TSHR (0.50)
SCHEMBL1004909 0.72
SCHEMBL28140 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
EP-2330908-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER Georgetown University (US) 2011-06-15 EP claimed
WO-2010019967-A1 FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER GEORGETOWN UNIVERSITY (US) 2010-02-18 WO claimed
CN-101113336-A Dimer liquid crystals compound with halogens on side UNIV YANBIAN (CN) 2008-01-30 CN claimed
US-7273948-B2 Process of preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS, INC. (US) 2007-09-25 US claimed
EP-1594824-A4 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS INC (US) 2007-04-04 EP claimed
EP-1594824-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF Atherogenics, Inc. (US) 2005-11-16 EP claimed
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof CRABTREE ACQUISITION CO, LLC 2004-10-14 US claimed
WO-2004062622-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS, INC. (US) 2004-07-29 WO claimed
US-6458962-B1 VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION 2002-10-01 US claimed
WO-2000056332-A1 SULTAMS: CATALYST SYSTEMS FOR ASYMMETRIC REDUCTION OF A C=N INTERMEDIATE BIOLOGICAL COMPOSITIONS AND METHODS FOR MAKING THE SULTAMS THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2000-09-28 WO claimed
JP-57134425-A None JP disclosed
US-12635409-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-05-19 US disclosed
US-12612379-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-04-28 US disclosed
US-20260035335-A1 PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed
EP-0019190-A2 Use of hydroxyalkyl-imidazoles as fungicides BAYER AG (DE) 1980-11-26 EP disclosed
EP-0011769-A1 Hydroxyethyl azoles, process for their preparation and their use in medicaments BAYER AG (DE) 1980-06-11 EP disclosed
US-3965112-A Imidazoline derivatives JOHN WYETH & BROTHER LIMITED (EN) 1976-06-22 US disclosed