Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694325 | 0.94 | LMNA (0.61) | LIG1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL3444937 | 0.92 | KMT2A (0.72) | LIG1KMT2AMAPTLMNAHPGD | |
| SCHEMBL10611136 | 0.90 | KMT2A (0.67) | LIG1KMT2AMAPK1ESR1ESR2 | |
| SCHEMBL2991958 | 0.86 | NR4A1 (0.69) | KMT2AMAPK1MAPTLMNAHPGD | |
| SCHEMBL29989484 | 0.86 | NR4A1 (0.69) | KMT2AMAPK1MAPTLMNAHPGD | |
| SCHEMBL29434816 | 0.85 | KMT2A (0.65) | KMT2AMAPTLMNAPKMHPGD | |
| SCHEMBL49873 | 0.85 | KMT2A (0.65) | KMT2AMAPTLMNAPKMHPGD | |
| SCHEMBL9614636 | 0.85 | LIG1 (0.79) | LIG1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL9409782 | 0.84 | NR4A1 (0.67) | KMT2AMAPK1MAPTLMNAHPGD | |
| SCHEMBL7120813 | 0.84 | KMT2A (0.64) | KMT2ACES2CES1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12172946-B2 | Compound containing diphenylmethane structure and use thereof | GUANGZHOU TROJAN PHARMATEC LTD. (CN) | 2024-12-24 | — | — | US | disclosed |
| US-20220002230-A1 | COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF | GUANGZHOU CONGEN PHARMATEC CO., LTD. (CN) | 2022-01-06 | — | — | US | disclosed |
| EP-3901132-A1 | COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF | Guangzhou Trojan Pharmatec Ltd. (CN) | 2021-10-27 | — | — | EP | disclosed |
| CN-110194724-B | Compound containing diphenylmethane structure and application thereof | 广州同隽医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2020143392-A1 | COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF | 广州同隽医药科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| CN-109369425-A | The preparation method of fenofibrate choline salt | 陕西威信制药有限公司 | 2019-02-22 | — | — | CN | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| EP-0386542-A2 | Process for preparation of aromatic polyetherketons | BAYER AG (DE) | 1990-09-12 | — | — | EP | disclosed |
| EP-0344688-A2 | Process for producing a phenolate and process for producing an aromatic polyether ketone employing it | MITSUBISHI KASEI CORPORATION (JP) | 1989-12-06 | — | — | EP | disclosed |
| EP-0307710-A1 | Process for producing aromatic polyether ketones | BAYER AG (DE) | 1989-03-22 | — | — | EP | disclosed |
| EP-0128693-B1 | PROCESS FOR THE PREPARATION OF 4-HYDROXYBENZOPHENONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |
| US-4711945-A | Polyketone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-08 | — | — | US | disclosed |
| US-4604485-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-05 | — | — | US | disclosed |
| EP-0182648-A2 | Process for the Preparation of Polyetherketones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-28 | — | — | EP | disclosed |
| EP-0128693-A2 | Process for the preparation of 4-hydroxybenzophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-19 | — | — | EP | disclosed |
| US-4153724-A | Benzoyl phenoxy acetic acid derivatives | KAKEN CHEMICAL CO., LTD. (JP) | 1979-05-08 | — | — | US | disclosed |
| US-3985783-A | Process for ring acylation of phenols | THE DOW CHEMICAL COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12172946-B2 | Compound containing diphenylmethane structure and use thereof | PEPD, VIP, DNPEP | LIG1 2913/4885KMT2A 3822/4885MAPK1 793/4885 |
| US-20220002230-A1 | COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF | PEPD, VIP, DNPEP | LIG1 2913/4885KMT2A 3822/4885MAPK1 793/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | LIG1 4039/4885KMT2A 2642/4885MAPK1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.