Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3444937 | 0.92 | KMT2A (0.72) | KMT2AALDH1A1NR4A1SRD5A2AKR1C3 | |
| SCHEMBL49873 | 0.90 | KMT2A (0.65) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| SCHEMBL29434816 | 0.90 | KMT2A (0.65) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| Hydrochloric Acid SCHEMBL4594710 | 0.88 | KMT2A (0.62) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| Hydrochloric Acid SCHEMBL4594716 | 0.88 | KMT2A (0.62) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| SCHEMBL27645699 | 0.88 | KMT2A (0.62) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| SCHEMBL11106514 | 0.86 | CDC25B (0.67) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| SCHEMBL30153497 | 0.86 | CDC25B (0.67) | KMT2AALDH1A1NR4A1AKR1C3CES2 | |
| SCHEMBL29989484 | 0.86 | NR4A1 (0.69) | KMT2AALDH1A1NR4A1SRD5A2CES2 | |
| SCHEMBL2991958 | 0.86 | NR4A1 (0.69) | KMT2AALDH1A1NR4A1SRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192845-A1 | THERMOCHROMIC COLOR-MEMORY COMPOSITION AND THERMOCHROMIC COLOR-MEMORY MICROCAPSULE PIGMENT INCLUDING SAME | THE PILOT INK CO., LTD. (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | KRISTIANSEN MARIT (DK) | 2003-10-02 | — | — | US | disclosed |
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186944-A1 | Such as 4-(2-(3-dimethylaminobenzoylamino)phenoxy)phthalic acid for treatment/prevention of diabetes; for inhibiting liver glycogen phosphorylase; dietetics | PYGL, GYS2, PYGM | KMT2A 971/4885ALDH1A1 901/4885NR4A1 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.