Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129444 | 0.85 | TDP1 (0.39) | CYP3A4TDP1ALDH1A1TP53PRKCZ | |
| SCHEMBL5388052 | 0.84 | SKP2 (0.41) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 | |
| Methane SCHEMBL28624868 | 0.83 | TDP1 (0.37) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL5382796 | 0.80 | SKP2 (0.40) | CYP3A4TDP1ALDH1A1TP53PRKCZ | |
| SCHEMBL5381204 | 0.79 | USP7 (0.37) | CYP3A4TDP1ALDH1A1TP53PRKCZ | |
| SCHEMBL820321 | 0.78 | RPS6KA3 (0.47) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL5382005 | 0.77 | ALDH1A1 (0.32) | CYP3A4TDP1ALDH1A1TP53PRKCZ | |
| SCHEMBL5437684 | 0.76 | RPS6KA3 (0.46) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 | |
| SCHEMBL5437685 | 0.76 | RPS6KA3 (0.46) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27683817 | 0.76 | RPS6KA3 (0.46) | RPS6KA3CYP3A4TDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | RPS6KA3 3109/4885CYP3A4 1456/4885TDP1 2646/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | RPS6KA3 3202/4885CYP3A4 1249/4885TDP1 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.