Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | PPARG | P37231 | 11/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575581 | 0.81 | PPARG (0.45) | PPARAPPARGEPHX2PPARDLDHA | |
| SCHEMBL5375683 | 0.81 | PPARG (0.45) | PPARAPPARGEPHX2PPARDLDHA | |
| SCHEMBL14392121 | 0.77 | PPARA (0.45) | PPARAPPARGEPHX2PPARDLDHA | |
| SCHEMBL5360147 | 0.77 | ESR1 (0.51) | PPARA | |
| SCHEMBL3694538 | 0.77 | ESR1 (0.51) | PPARA | |
| SCHEMBL14560652 | 0.77 | PPARA (0.56) | PPARAPPARGPPARDACACBKMT2A | |
| SCHEMBL5360137 | 0.76 | PPARA (0.55) | PPARAPPARGPPARDKMT2A | |
| SCHEMBL4085094 | 0.76 | LMNA (0.49) | PPARAPPARGEPHX2PPARD | |
| SCHEMBL14392081 | 0.76 | MMP8 (0.40) | PPARAPPARGEPHX2PPARDLDHA | |
| SCHEMBL5381299 | 0.76 | APEX1 (0.40) | PPARAPPARGEPHX2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | PPARA 3/4885PPARG 2/4885EPHX2 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.