Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11382581 | 0.98 | MAPT (0.51) | MAPTSRCMMP8POLBKMT2A | |
| SCHEMBL4068945 | 0.87 | MAPT (0.43) | MAPTSRCMMP8POLBKMT2A | |
| SCHEMBL11377804 | 0.87 | MAPT (0.43) | MAPTSRCALDH1A1HSD17B10LMNA | |
| SCHEMBL5165789 | 0.86 | MAPT (0.43) | MAPTMMP8KMT2AALDH1A1 | |
| SCHEMBL4281827 | 0.86 | MAPT (0.43) | MAPTSRCMMP8POLBNPC1 | |
| SCHEMBL1155256 | 0.86 | POLB (0.44) | MAPTPOLBKMT2AMEN1LMNA | |
| SCHEMBL290365 | 0.84 | ALDH1A1 (0.43) | MAPTMMP8POLBNPC1ALDH1A1 | |
| SCHEMBL11623149 | 0.83 | MAPT (0.41) | MAPTSRCNPC1ALDH1A1LMNA | |
| SCHEMBL18978192 | 0.83 | MMP8 (0.48) | SRCMMP8POLBKMT2AMEN1 | |
| SCHEMBL8860210 | 0.82 | SRC (0.59) | SRCMMP8KMT2AKLK7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092709-B | Synthetic method of non-urethane intermediate 2-phenyl-1, 3-propylene glycol | 深圳市第二人民医院 | 2022-03-04 | — | — | CN | claimed |
| CN-113603589-A | Method for purifying diethyl phenylmalonate | 山东石大胜华化工集团股份有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-110092709-B | Synthetic method of non-urethane intermediate 2-phenyl-1, 3-propylene glycol | 深圳市第二人民医院 | 2022-03-04 | — | — | CN | disclosed |
| CN-113603589-A | Method for purifying diethyl phenylmalonate | 山东石大胜华化工集团股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| US-20120077810-A1 | Inhibitors Of AKT Activity | MERCK SHARP & DOHME LLC | 2012-03-29 | — | — | US | disclosed |
| EP-2413932-A1 | INHIBITORS OF AKT ACTIVITY | Merck Sharp & Dohme Corp. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114780-A1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. | 2010-06-24 | — | — | US | disclosed |
| US-7625948-B2 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2009-12-01 | — | — | US | disclosed |
| EP-1888570-A2 | METHODS FOR SYNTHESIS OF DICARBAMATE COMPOUNDS AND INTERMEDIATES IN THE FORMATION THEREOF | MedPointe Healthcare Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006116007-A2 | METHODS FOR SYNTHESIS OF DICARBAMATE COMPOUNDS AND INTERMEDIATES IN THE FORMATION THEREOF | MEDPOINTE HEALTHCARE INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| US-4118562-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1978-10-03 | — | — | US | disclosed |
| US-4093802-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4093804-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4066664-A | Intermediates for preparing α-carboxy-α-(3-thienyl)penicillin and cephalosporin derivatives | RECHERCHE ET INDUSTRIE THERAPEUTIQUES (BE) | 1978-01-03 | — | — | US | disclosed |
| US-4045438-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1977-08-30 | — | — | US | disclosed |
| US-4031083-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1977-06-21 | — | — | US | disclosed |
| US-4026887-A | Cephalosporin antibiotics | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1977-05-31 | — | — | US | disclosed |
| US-3994875-A | CEPHALOSPORINS, PENICILLINS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-11-30 | — | — | US | disclosed |
| US-3948904-A | ANTIBIOTICS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158996-A1 | ESTER COMPOUND AND MEDICAL USE THEREOF | LIPC, CES1, MTTP | MAPT 4163/4885SRC 2497/4885MMP8 2623/4885 |
| US-20120077810-A1 | Inhibitors Of AKT Activity | PIK3CA, PIK3CD, PIK3CB | MAPT 4496/4885SRC 254/4885MMP8 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.